1290127-70-6

Usage

Uses

Used in Pharmaceutical Research:
1-(4-bromo-3,5-dimethoxyphenyl)ethanol is used as a research compound for the synthesis of various organic compounds, particularly those with potential pharmacological applications. Its structural similarity to mescaline makes it a valuable starting point for the development of new drugs with similar or improved properties.
Used in Chemical Synthesis:
In the chemical industry, 1-(4-bromo-3,5-dimethoxyphenyl)ethanol is used as a precursor in the synthesis of other complex organic molecules. Its unique functional groups and structural features allow for a wide range of chemical reactions, making it a versatile building block for the creation of novel compounds.
Used in Medicinal Chemistry:
1-(4-bromo-3,5-dimethoxyphenyl)ethanol is used as a starting material in medicinal chemistry for the development of new drugs. Its structural features can be modified to create compounds with specific biological activities, potentially leading to the discovery of new therapeutic agents.
Used in Neuropharmacology:
Due to its structural relationship with mescaline, 1-(4-bromo-3,5-dimethoxyphenyl)ethanol is used in neuropharmacological research to study the effects of hallucinogenic substances on the central nervous system. This research can provide insights into the mechanisms of action of these compounds and may contribute to the development of new treatments for neurological and psychiatric disorders.

Upstream product

• 31558-40-4 4-bromo-3,5-dimethoxybenzaldehyde 
• 75-16-1 methylmagnesium bromide 
• 61367-62-2 (4-bromo-3,5-dimethoxyphenyl)methanol 
• 917-54-4 methyllithium 
• 56518-42-4 4-bromo-3,5-dimethoxybenzoic acid 

Downstream Products

• 1290127-71-7 2-bromo-1,3-dimethoxy-5-(1-methoxyethyl)benzene 
• 1290127-72-8 [2,6-Dimethoxy-4-(1-methoxyethyl)phenyl]boronic acid 
• 1333471-25-2 1-(4-(4-bromo-3,5-dimethoxyphenyl)thiazol-2-yl)-2-methoxy-2-(4-morpholinophenyl)ethanone 
• 1333471-26-3 1-(4-(4-bromo-3,5-dimethoxyphenyl)oxazol-2-yl)-2-methoxy-2-(4-morpholinophenyl)-ethanone 
• 1333472-31-3 4-(4-bromo-3,5-dimethoxyphenyl)oxazole 
• 1333471-27-4 2-(4-(1H-pyrazol-1-yl)phenyl)-1-(4-(4-bromo-3,5-dimethoxyphenyl)thiazol-2-yl)-2-methoxyethanone 
• 1333472-30-2 4-(4-bromo-3,5-dimethoxyphenyl)thiazole 
• 1333472-29-9 2-bromo-1-(4-bromo-3,5-dimethoxyphenyl)ethanone 
• 1333472-28-8 1-(4-bromo-3,5-dimethoxyphenyl)ethanone 

Relevant academic research and scientific papers

PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METHODS

Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.

PYRAZOLOTHIAZOLE COMPOUND

A compound represented by the formula (I) or pharmacologically acceptable salt thereof exhibits an excellent CRF receptor antagonism wherein X is a nitrogen atom or CH; R1 is -A11-A12; A11 is a single bond or a C1-6 alkylene group; A12 is a hydrogen atom, a C1-6 alkyl group or a C3-6 cycloalkyl group, etc.; R2 is -A21-A22; A21 is a single bond or a C1-6 alkylene group; A22 is a hydrogen atom, a C1-6 alkyl group, a C3-6 cycloalkyl group, a non-aromatic heterocyclic group, or a heteroaryl group, etc.; R3 is a C 1-6 alkyl group, a C3-6 cycloalkyl group, a C1-6 alkoxy group, a C3-6 cycloalkoxy C1-6 alkyl group, di-C1-6 alkyl amino group, a halogen atom, a cyano group, a formyl group, or a carboxyl group, etc; R4 is a hydrogen atom or a C1-6 alkoxy group; R5 is a halogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group; R6 is a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, a C1-6 alkylthio group, or a C1-6 alkyl sulfinyl group etc.; and R7 is a C1-6 alkyl group, a C1-6 alkoxy group, or a C1-6 alkylthio group