129053-83-4

Basic information

• Product Name: ETHYL 3-[(1H-PYRROLE-2-CARBONYL)-AMINO]PROPIONATE
• Synonyms: ETHYL 3-[(1H-PYRROLE-2-CARBONYL)-AMINO]PROPIONATE;Ethyl 3-(1H-pyrrole-2-carboxaMido)propanoate
• CAS NO: 129053-83-4
• Molecular Formula: C₁₀H₁₄N₂O₃
• Molecular Weight: 210.23
• Mol File: 129053-83-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 3-[(1H-PYRROLE-2-CARBONYL)-AMINO]PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-[(1H-PYRROLE-2-CARBONYL)-AMINO]PROPIONATE(129053-83-4)
• EPA Substance Registry System: ETHYL 3-[(1H-PYRROLE-2-CARBONYL)-AMINO]PROPIONATE(129053-83-4)

Safety Data

• Hazardous Substances Data: 129053-83-4(Hazardous Substances Data)

Upstream product

• 4244-84-2 ethyl β-alaninate hydrochloride 
• 634-97-9 pyrrole-2-carboxyl acid 
• 109-97-7 pyrrole 
• 924-73-2 3-amino-propionic acid ethyl ester 
• 503-38-8 trichloromethyl chloroformate 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 

Downstream Products

• 1413996-17-4 (E)-4-(benzyloxyimino)-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one 
• 1233710-91-2 C₂₁H₂₅BN₂O₄ 
• 1233710-92-3 C₁₅H₁₃BrN₂O₂ 
• 1323444-44-5 C₂₇H₂₅N₅O₂ 
• 1234505-95-3 C₂₃H₂₂N₂O₃ 
• 1323444-43-4 C₂₁H₁₉N₃O₂ 
• 1323444-42-3 C₂₁H₁₈N₂O₃ 
• 1323444-41-2 C₂₂H₁₉N₃O₃ 
• 1323444-40-1 C₂₂H₁₇N₃O₂ 
• 1233710-90-1 C₂₅H₂₆N₂O₃ 
• 1234505-94-2 C₂₄H₂₄N₂O₃ 
• 1234505-93-1 C₂₄H₂₄N₂O₃ 
• 1234505-92-0 C₂₃H₂₂N₂O₃ 
• 1234505-91-9 C₂₂H₂₀N₂O₃ 

Relevant articles and documents

Synthesis and antibacterial evaluation of (E)-1-(1H-indol-3-yl) ethanone O-benzyl oxime derivatives against MRSA and VRSA strains

Infections caused due to multidrug resistant organisms have emerged as a constant menace to human health. Even though numerous antibiotics are currently available for treating infectious diseases, a great number of bacterial strains have acquired resistance to many of them. Among these, infections caused due to Staphylococcus aureus are predominant in adult and paediatric population. Indole is a prominent chemical scaffold found in many pharmacologically active natural products and synthetic drugs. A number of oxime ether containing compounds have attracted attention of researchers owing to their interesting biological properties. Current work details the synthesis of indole containing oxime ether derivatives and their evaluation for antimicrobial activity against a panel of bacterial and mycobacterial strains. Synthesized compounds demonstrated good to moderate activity against drug-resistant S. aureus including resistant to vancomycin. Among all, compound 5h was found to possess potent activity against susceptible as well as MRSA and VRSA strains of S. aureus with MIC of 1 μg/mL and 2–4 μg/mL respectively. In addition, compound 5h was found to be non-toxic to Vero cells and exhibited good selectivity index of >40. Further, 5h, E-9a and E-9b possessed good biofilm inhibition against S. aureus. With these assuring biological properties, synthesized compounds could be potential prospective antimicrobial agents.

Pyrrolo[2,3-c]azepine derivatives: A new class of potent protein tyrosine phosphatase 1B inhibitors

A series of pyrrolo[2,3-c]azepine derivatives was designed, synthesized, and evaluated as a new class of inhibitors against protein tyrosine phosphatase 1B (PTP1B) in vitro. The results demonstrated that compounds bearing a biphenyl moiety were proved to

WNT SIGNALING INHIBITORS, AND METHODS FOR MAKING AND USING THEM

The invention provides dBHD-based compositions and dBHD analog compositions, and pharmaceutical compositions comprising them, e.g., in the form of liposomes and nanoparticles comprising them, and methods of making and using them. In one embodiment, these dBHD analogs are used to inhibit a dysfunctional stem cell and/or a cancer (tumor) stem cell.