1291083-48-1

Upstream product

• 271600-36-3 N-[phenyl(toluene-4-sulfonyl)methyl]tert-butoxycarboxyamide 
• 4248-19-5 tert-butyl carbazate 

Downstream Products

• 1291083-49-2 tert-butyl (1R,2R)-5-(tert-butyldimethylsilyloxy)-2-hydroxy-1-phenylpentylcarbamate 
• 1291083-50-5 tert-butyl (1R,2R)-2-(3,5-bis(trifluoromethyl)benzyloxy)-5-(tert-butyldimethylsilyloxy)-1-phenylpentylcarbamate 
• 1313494-66-4 C₂₅H₂₉F₆NO₄ 
• 148700-91-8 L 733061 

Relevant academic research and scientific papers

Enantioselective N-H insertion reaction of α-aryl α-diazoketones: An efficient route to chiral α-aminoketones

A highly enantioselective N-H insertion reaction of α-diazoketones was developed by using cooperative catalysis by dirhodium(II) carboxylates and chiral spiro phosphoric acids. The insertion reaction provides a new access route to diverse chiral α-aminoketones, which are versatile building blocks in organic synthesis, with fast reaction rates, good yields and high enantioselectivity under mild and neutral conditions. Spiro inspiration: A highly enantioselective N-H insertion reaction of α-diazoketones was developed by using cooperative catalysis by dirhodium(II) carboxylates and chiral spiro phosphoric acids. The insertion reaction provides a new access route to diverse chiral α-aminoketones, which are versatile building blocks in the organic synthesis, with fast reaction rates, good yields and high enantioselectivity under mild and neutral conditions.

A concise enantioselective synthesis of L-(-)-733,061 and (2S,3S)-methyl 3-aminopiperidine-2-carboxylate using catalytic enantioselective aza-Henry reaction as key step

An efficient enantioselective synthesis of L-(-)-733,061 and (2S,3S)-methyl 3-aminopiperidine-2-carboxylate is accomplished by means of catalytic enantioselective aza-Henry reaction. A key feature of this protocol is organocatalysis as genesis of chiralit