1291101-88-6Relevant academic research and scientific papers
Formal asymmetric synthesis of echinopine A and B
Peixoto, Philippe A.,Severin, Rene,Tseng, Chih-Chung,Chen, David Y.-K.
, p. 3013 - 3016 (2011)
(Chemical Equation Presented) Enticing structures: The formal syntheses of 1 and 2 were accomplished by using a cascade strategy involving an enyne cycloisomerization reaction and an intramolecular Diels-Alder reaction starting from 3. The resulting 4 underwent a late-stage ring contraction to enable the preparation of a reported advanced intermediate, thereby constituting a formal synthesis of the structurally intriguing title compounds.
Total synthesis of echinopines A and B: Exploiting a bioinspired late-stage intramolecular cyclopropanation
Peixoto, Philippe A.,Richard, Jean-Alexandre,Severin, Rene,Chen, David Y.-K.
, p. 5724 - 5727 (2011)
Total synthesis of echinopine A and B have been accomplished, based on a strategy that involved two transition-metal-mediated ene-yne cycloisomerizations. A modified Pd-catalyzed enyne cycloisomerization/ intramolecular Diels-Alder cascade rendered a more
