129145-53-5 Usage
Explanation
This is the scientific name of the chemical compound, which is derived from its structural formula.
Explanation
Luteolin is the commonly used name for 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-[(2E)-3-methylpent-2-en-1-yl]-4H-chromen-4-one, making it easier to refer to in conversations and research.
Explanation
Luteolin is classified as a flavonoid, which is a group of naturally occurring compounds found in various plants.
Explanation
Luteolin can be found in various plants, including fruits, vegetables, and herbs.
Explanation
Luteolin possesses multiple beneficial properties, such as antioxidant (neutralizing harmful free radicals), anti-inflammatory (reducing inflammation), and anticancer (inhibiting cancer cell growth).
Explanation
Research has shown that luteolin may help protect against several diseases, including heart-related conditions, diseases that affect the nervous system, and cancer.
Explanation
Luteolin has also been found to exhibit antimicrobial (fighting against microorganisms like bacteria and fungi) and neuroprotective (protecting nerve cells from damage) effects.
Explanation
Due to its wide range of health benefits, luteolin has significant potential for use in pharmaceutical and medicinal products.
Classification
Flavonoid
Occurrence
Naturally occurring in plants
Properties
Antioxidant, anti-inflammatory, and anticancer
Potential Health Benefits
Protection against cardiovascular diseases, neurodegenerative disorders, and cancer
Additional Effects
Antimicrobial and neuroprotective
Applications
Pharmaceutical and medicinal
Check Digit Verification of cas no
The CAS Registry Mumber 129145-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,1,4 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 129145-53:
(8*1)+(7*2)+(6*9)+(5*1)+(4*4)+(3*5)+(2*5)+(1*3)=125
125 % 10 = 5
So 129145-53-5 is a valid CAS Registry Number.
129145-53-5Relevant academic research and scientific papers
Li, Jianhua,Chen, Ridao,Wang, Ruishan,Liu, Xiao,Xie, Dan,Zou, Jianhua,Dai, Jungui
, p. 1673 - 1681 (2014)
GuA6DT, a flavonoid prenyltransferase, was identified from Glycyrrhiza uralensis, and it was found that this enzyme regiospecifically transfers a dimethylallyl moiety to apigenin at the C-6 position. A further substrate specificity investigation indicated that the existence of hydroxyls at both the C-5 and C-7 positions of the flavone skeleton is critical for the prenylation. However, substitutions on the B-ring had negligible influence on the prenylation. A comparison of GuA6DT expression in different organs revealed that mRNA is mainly expressed in the aerial parts. Moreover, the GuA6DT mRNA was found to be regulated at the transcriptional level, because methyl jasmonate induced upregulation in cultured cells. GuA6DT is the first identified flavone prenyltransferase to exhibit strict substrate specificity and regiospecificity.
Pharmacophore identification, virtual screening and biological evaluation of prenylated flavonoids derivatives as PKB/Akt1 inhibitors
Dong, Xiaowu,Zhou, Xinglu,Jing, Hui,Chen, Jianzhong,Liu, Tao,Yang, Bo,He, Qiaojun,Hu, Yongzhou
, p. 5949 - 5958 (2012/02/01)
A total of 24 well-defined PKB/Akt1 inhibitors were used to generate pharmacophore models applying Catalyst/HypoGen program. The best ranked model (Hypo-1) was then validated by cost analysis, prediction capability, Cat-Scramble and receiver operating cha
