129155-87-9Relevant academic research and scientific papers
Origin of the stereospecificity in binding hydroxamates of α- and β-phenylalanine methylamide to thermolysin revealed by the X-ray crystallographic study
Kim, Seung-Jun,Kim, Dong H.,Park, Jung Dae,Woo, Joo-Rang,Jin, Yonghao,Ryu, Seong Eon
, p. 2421 - 2426 (2007/10/03)
Optically active N-formyl-N-hydroxy-α-phenylalanine methylamide (1) and N-formyl-N-hydroxy-β-phenylalanine methylamide (2) were evaluated as inhibitors for thermolysin (TLN) to find that while the D-form is more potent than its enantiomer in the case of t
OXIDATIVE PREPARATION OF OPTICALLY ACTIVE N-HYDROXY-α-AMINO ACID AMIDES
Feenstra, R. W.,Stokkingreef, E. H. M.,Reichwein, A. M.,Lousberg, W. B. H.,Ottenheijm, H. C. J.,et al.
, p. 1745 - 1756 (2007/10/02)
Two routes are presented for the conversion of optically active α-amino acid amides into the title compounds.One route (route A) features the formation of the Schiff's base 6 which is subsequently oxidized to the corresponding oxaziridines 7.Route B is ch
