683240-15-5Relevant academic research and scientific papers
Origin of the stereospecificity in binding hydroxamates of α- and β-phenylalanine methylamide to thermolysin revealed by the X-ray crystallographic study
Kim, Seung-Jun,Kim, Dong H.,Park, Jung Dae,Woo, Joo-Rang,Jin, Yonghao,Ryu, Seong Eon
, p. 2421 - 2426 (2003)
Optically active N-formyl-N-hydroxy-α-phenylalanine methylamide (1) and N-formyl-N-hydroxy-β-phenylalanine methylamide (2) were evaluated as inhibitors for thermolysin (TLN) to find that while the D-form is more potent than its enantiomer in the case of t
