1292297-90-5

Upstream product

• 1026024-89-4 (S)-5-[(4-methoxybenzyl)oxy]pentane-1,2-diol 
• 131375-69-4 5-((4-methoxybenzyl)oxy)pentanal 
• 726193-03-9 (S)-ethyl 3-(1,4-dioxaspiro[4.5]decan-2-yl)propanoate 
• 726193-04-0 (S)-3-(1,4-dioxaspiro[4.5]decan-2-yl)propan-1-ol 
• 112980-46-8 ethyl (2'S)-3-(1',4'-dioxa-spiro[4.5]dec-2'-yl)-acrylate 
• 1292297-89-2 (S)-2-[3-(4-methoxybenzyloxy)propyl]-1,4-dioxaspiro[4.5]decane 

Downstream Products

• 1292297-92-7 [(S)-7-(4-Methoxybenzyloxy)hept-1-en-4-yloxy](tert-butyl)dimethylsilane 
• 1292297-96-1 (S)-[(2R,3R)-3-(benzyloxy)pent-4-en-2-yl] 4-(tert-butyldimethylsilyloxy)hept-6-enoate 
• 1292297-97-2 (S)-[(2R,3R)-3-(benzyloxy)pent-4-en-2-yl] 4-hydroxyhept-6-enoate 
• 1292297-98-3 (Z,5S,9R,10R)-9-(benzyloxy)-3,4,5,6,9,10-hexahydro-5-hydroxy-10-methyloxecin-2-one 
• 1292297-91-6 (S)-7-(4-methoxybenzyloxy)hept-1-en-4-ol 
• 1349725-50-3 C₂₀H₃₄O₃Si 
• 1571059-44-3 (S)-6-(4-methoxybenzyloxy)hex-1-en-3-ol 
• 1408237-20-6 (S)-4-[(tert-butyldiphenylsilyl)oxy]hex-5-enoic acid 
• 1408237-21-7 (2R,4S)-4-[(tert-butyldiphenylsilyl)oxy]hex-5-en-2-yl (S)-4-[(tert-butyldiphenylsilyl)oxy]hex-5-enoate 

Relevant academic research and scientific papers

Synthesis of Ophiocerins A, B and C, Botryolide E, Decarestrictine O, Stagonolide C and 9-epi-Stagonolide C Employing Chiral Hexane-1,2,3,5-tetraol Derivatives as Building Blocks

An organocatalytic approach to the synthesis of (2R,3S)-hexane-1,2,3,5-tetraol (11) derivatives (in the forms of different stereoisomers and bearing different protecting groups) has been developed. The key chiral intermediates 11 were prepared with complete stereocontrol through the proline-catalyzed intermolecular aldol reaction between acetone and d-glyceraldehyde acetonide. The synthetic utility of the intermediates was demonstrated by their transformation into the title hydroxylated pyrans and a variety of unsaturated lactones through standard synthetic protocols.

Stereoselective Synthesis of Stagonolide G from d -Mannitol

A highly convergent, stereoselective total synthesis of a ten-membered lactone, stagonolide G, is described. Epoxide ring-opening with vinyl Grignard, Yamaguchi esterification and ring-closing metathesis are the key steps involved in the present approach.