1292297-92-7

Upstream product

• 1292297-91-6 (S)-7-(4-methoxybenzyloxy)hept-1-en-4-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 
• 119649-45-5 4-(p-methoxybenzyloxy)butan-1-ol 
• 119649-27-3 4-((4-methoxybenzyl)oxy)butanal 
• 726193-03-9 (S)-ethyl 3-(1,4-dioxaspiro[4.5]decan-2-yl)propanoate 
• 726193-04-0 (S)-3-(1,4-dioxaspiro[4.5]decan-2-yl)propan-1-ol 
• 112980-46-8 ethyl (2'S)-3-(1',4'-dioxa-spiro[4.5]dec-2'-yl)-acrylate 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 1292297-90-5 (S)-2-{3-[(4-methoxybenzyl)oxy]propyl}oxirane 
• 1292297-89-2 (S)-2-[3-(4-methoxybenzyloxy)propyl]-1,4-dioxaspiro[4.5]decane 
• 1026024-89-4 (S)-5-[(4-methoxybenzyl)oxy]pentane-1,2-diol 

Downstream Products

• 1292297-96-1 (S)-[(2R,3R)-3-(benzyloxy)pent-4-en-2-yl] 4-(tert-butyldimethylsilyloxy)hept-6-enoate 
• 1292297-97-2 (S)-[(2R,3R)-3-(benzyloxy)pent-4-en-2-yl] 4-hydroxyhept-6-enoate 
• 1292297-98-3 (Z,5S,9R,10R)-9-(benzyloxy)-3,4,5,6,9,10-hexahydro-5-hydroxy-10-methyloxecin-2-one 
• 1269803-20-4 (S)-((4R,8R)-9-(benzyloxy)-8-methyl-6-methylenenonan-4-yl)-6-((2S,3S,5R)-5-(2-(4-methoxybenzyloxy)ethyl)-3-methyltetrahydrofuran-2-yl)-2-methylhexanoate 
• 1420766-79-5 (S)-4-benzyl-3-((2R,6R)-6-(tert-butyldimethylsilyloxy)-2-methyl-4-methylenenonanoyl)oxazolidin-2-one 
• 1269803-22-6 ((4R,8R)-9-(benzyloxy)-8-methyl-6-methylenenonan-4-yloxy)(tert-butyl)dimethylsilane 
• 1269803-12-4 (4R,8R)-9-(benzyloxy)-8-methyl-6-methylenenonan-4-ol 

Relevant academic research and scientific papers

Formal synthesis of amphidinin B

An efficient, convergent, and highly stereoselective formal synthesis of amphidinin B (1) is reported herein. In Amphidinin B both C10-C21 (4) and C1-C9 (5) fragments were derived from geraniol 6 and mono-PMB ether of 1,4-butane diol 7 in 19 and 9 steps, respectively. The key steps involved in this synthesis are Sharpless asymmetric epoxidation, Evans aldol, Julia olefination, oxa-Michael, Keck allylation, Mannich reaction, Evans asymmetric alkylation, and Yamaguchi esterification.

Asymmetric synthesis of stagonolide-D and stagonolide-G

First asymmetric synthesis of the naturally occurring epoxy noneolide stagonolide-D has been reported in this article. Ring-closing metathesis (RCM) by Grubbs second generation catalyst, Sharpless asymmetric epoxidation (SAE), and cis-selective HornerWads

Stereoselective Synthesis of Stagonolide G from d -Mannitol

A highly convergent, stereoselective total synthesis of a ten-membered lactone, stagonolide G, is described. Epoxide ring-opening with vinyl Grignard, Yamaguchi esterification and ring-closing metathesis are the key steps involved in the present approach.