1292814-42-6Relevant articles and documents
Synthesis and proteasome inhibition of lithocholic acid derivatives
Dang, Zhao,Lin, Andrew,Ho, Phong,Soroka, Dominique,Lee, Kuo-Hsiung,Huang, Li,Chen, Chin-Ho
supporting information; experimental part, p. 1926 - 1928 (2011/05/02)
A new class of proteasome inhibitors was synthesized using lithocholic acid as a scaffold. Modification at the C-3 position of lithocholic acid with a series of acid acyl groups yielded compounds with a range of potency on proteasome inhibition. Among the