129306-13-4

Basic information

• Product Name: 5-phenylmethyl-N-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-7-amine
• Synonyms: 5-phenylmethyl-N-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-7-amine
• CAS NO: 129306-13-4
• Molecular Weight: 302.417
• Mol File: 129306-13-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-phenylmethyl-N-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-7-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenylmethyl-N-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-7-amine(129306-13-4)
• EPA Substance Registry System: 5-phenylmethyl-N-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-7-amine(129306-13-4)

Safety Data

• Hazardous Substances Data: 129306-13-4(Hazardous Substances Data)

Upstream product

• 129306-04-3 5-benzyl-5-azaspiro[2.4]heptane-4,7-dione 
• 129306-06-5 (7E)-5-benzyl-7-(hydroxyimino)-5-azaspiro[2.4]heptan-4-one 
• 129306-07-6 5-benzyl-5-azaspiro[2.4]heptane-7-amine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 152513-88-7 (7S)-5-aza-7-tert-butoxycarbonylaminospiro[2.4]heptan 

Relevant articles and documents

Substituted alkynyl pyridine compounds and methods of use thereof, and use thereof

The invention provides a substituted alkynylpyridine compound with a structure represented by a formula (I) as described in the specification and a pharmaceutically acceptable salt and a medicinal preparation thereof. The compound is used for adjusting activity of protein kinase and adjusting intercellular or intracellular signal response. The invention also relates to a pharmaceutical composition including the compound provided by the invention and a method of applying the pharmaceutical composition in treating mammals, especially in treating highly proliferative diseases of the mankind.

Synthesis and In-Vitro Activity of Novel 1β-Methylcarbapenems Having Spiro[2,4]heptane Moieties

The synthesis of a new series of 1β-methylcarbapenems having spiro[2,4]heptane moieties is described. Their in-vitro antibacterial activities against both gram-positive and gram-negative bacteria were tested and the effect of substituents on the pyrrolidine ring was investigated. Most compounds were shown to be more active than the compared meropenem and imipenem against Escherichia coli. One particular compound, IIIb, having hydroxy a moiety showed the most potent antibacterial activity.