1293323-83-7

Basic information

• Product Name: (2-bromo-4-fluorobenzyl)(cyclohex-2-enyl)carbamic acid tert-butyl ester
• Synonyms: (2-bromo-4-fluorobenzyl)(cyclohex-2-enyl)carbamic acid tert-butyl ester
• CAS NO: 1293323-83-7
• Molecular Weight: 384.289
• Mol File: 1293323-83-7.mol

Chemical Properties

• CAS DataBase Reference: (2-bromo-4-fluorobenzyl)(cyclohex-2-enyl)carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-4-fluorobenzyl)(cyclohex-2-enyl)carbamic acid tert-butyl ester(1293323-83-7)
• EPA Substance Registry System: (2-bromo-4-fluorobenzyl)(cyclohex-2-enyl)carbamic acid tert-butyl ester(1293323-83-7)

Safety Data

• Hazardous Substances Data: 1293323-83-7(Hazardous Substances Data)

Upstream product

• 1006-41-3 2-bromo-4-fluorobenzoic acid 
• 1006-40-2 2-bromo-4-fluorobenzamide 
• 36282-26-5 2-bromo-4-fluorobenzonitrile 
• 1521-51-3 rac-3-bromocyclohexene 
• 289038-14-8 2-bromo-4-fluorobenzylamine hydrochloride 

Relevant articles and documents

Rapid synthesis and zebrafish evaluation of a phenanthridine-based small molecule library

A Heck cyclisation approach is described for the rapid synthesis of a library of natural product-like small molecules, based on the phenanthridine core. The synthesis of a range of substituted benzylamine building blocks and their incorporation into the library is reported, together with a highly selective cis-dihydroxylation protocol that enables access to the target compounds in an efficient manner. Biological evaluation of the library using zebrafish phenotyping has led to the discovery of compound 20c, a novel inhibitor of early-stage zebrafish embryo development.