1293990-77-8

Basic information

• Product Name: 7-methyl-2,3-diphenylisoquinolin-1(2H)-one
• Synonyms: 7-methyl-2,3-diphenylisoquinolin-1(2H)-one
• CAS NO: 1293990-77-8
• Molecular Weight: 311.383
• Mol File: 1293990-77-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 7-methyl-2,3-diphenylisoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-2,3-diphenylisoquinolin-1(2H)-one(1293990-77-8)
• EPA Substance Registry System: 7-methyl-2,3-diphenylisoquinolin-1(2H)-one(1293990-77-8)

Safety Data

• Hazardous Substances Data: 1293990-77-8(Hazardous Substances Data)

Upstream product

• 10335-81-6 3-methylphenylhydroxamic acid 
• 501-65-5 diphenyl acetylene 
• 618-47-3 m-toluamide 
• 33341-66-1 N-chloro-3-methylbenzamide 
• 13050-47-0 3-methylbenzoyl hydrazine 
• 96963-49-4 3-methyl-N-(naphthalen-1-yl)benzamide 
• 72755-11-4 N-methoxy-3-methylbenzamide 
• 99-04-7 m-Toluic acid 
• 1711-06-4 3-Methylbenzoyl chloride 
• 1293990-76-7 N-tert-pentanoyloxy-m-methylbenzamide 

Downstream Products

• 1280681-79-9 C₃₂H₂₅NO₃ 
• 1253388-68-9 10-methyl-5,6,13-triphenyl-8H-isoquinolino[3,2-a]isoquinolin-8-one 

Relevant articles and documents

Synthesis of isoquinolone via rhodium(III)-catalyzed C-H activation with 1,4,2-dioxazol-5-ones as oxidizing directing group

An efficient rhodium-catalyzed direct C-H activation for the synthesis of isoquinolone with 1,4,2-dioxazol-5-ones as oxidizing directing groups have been developed, which featured mild reaction conditions, short reaction time and satisfactory yield.

Palladium-Catalyzed Inert C?H Bond Activation and Cyclocarbonylation of Isoquinolones with Carbon Dioxide Leading to Isoindolo[2,1-b]isoquinoline-5,7-Diones

A palladium-catalyzed inert C?H bond activation and cyclocarbonylation of isoquinolones leading to isoindolo[2,1-b]isoquinoline-5,7-diones under 1 atm of carbon dioxide has been developed. This transformation features high regio- and chemo-selectivity, step-economy, and good functional group tolerance. Most of the corresponding products were obtained in moderate to good yields. It offers an alternative approach for the synthesis of useful diverse isoindolo[2,1-b]isoquinoline-5,7-dione derivatives. (Figure presented.).

Direct access to cobaltacycles via C-H activation: N-chloroamide- enabled room-temperature synthesis of heterocycles

Cobaltacycle synthesis via C-H activation has been achieved for the first time, providing key mechanistic insight into cobalt catalytic chemistry. NChloroamides are used as a directing synthon for cobalt-catalyzed roomtemperature C-H activation and construction of heterocycles. Alkynes as coupling partners allow convenient access to isoquinolones, a class of synthetically and pharmaceutically important compounds. The broad substrate scope enables a diverse range of substitution patterns to be incorporated into the heterocyclic scaffold.