1294-29-7Relevant academic research and scientific papers
N-ortho-Ferrocenyl benzoyl dipeptide esters: Synthesis, structural characterization and in vitro anti-cancer activity of N-{ortho-(ferrocenyl)benzoyl}-glycine-l-alanine ethyl ester and N-{ortho-(ferrocenyl)benzoyl}-l-alanine-glycine ethyl ester
Corry, Alan J.,Goel, Alok,Alley, Steven R.,Kelly, Paula N.,O'Sullivan, Dermot,Savage, David,Kenny, Peter T.M.
, p. 1405 - 1410 (2007)
N-ortho-ferrocenyl benzoyl dipeptide esters 2-6 were prepared by coupling ortho-ferrocenyl benzoic acid 1 to the dipeptide ethyl esters GlyGly(OEt) (2), GlyAla(OEt) (3), GlyPhe(OEt) (4), AlaGly(OEt) (5) and AlaPhe(OEt) (6). The compounds were fully characterized by a range of NMR spectroscopic techniques, mass spectrometry and cyclic voltammetry. The cytotoxicity of 3 and 5 towards lung cancer cells has been determined.
Synthesis, characterization and in vitro anti-cancer activity of N-(ferrocenyl)benzoyl tri- and tetrapeptide esters
Corry, Alan J.,Mooney, áine,O'Sullivan, Dermot,Kenny, Peter T.M.
, p. 2957 - 2961 (2009/09/26)
N-ortho, N-meta and N-para-(ferrocenyl)benzoyl tri- and tetrapeptide esters (2-7) were prepared by coupling ortho, meta and para-ferrocenyl benzoic acids to the tri- and tetrapeptide ethyl esters of GlyGlyGly(OEt) and GlyGlyGlyGly(OEt) in the presence of
The synthesis and structural characterization of N-ortho-ferrocenyl benzoyl amino acid esters. The X-ray crystal structure of N-{ortho-(ferrocenyl)benzoyl} -l-phenylalanine ethyl ester
Savage, David,Malone, Gwen,Alley, Steven R.,Gallagher, John F.,Goel, Alok,Kelly, Paula N.,Mueller-Bunz, Helge,Kenny, Peter T.M.
, p. 463 - 469 (2007/10/03)
A series of N-ortho-ferrocenyl benzoyl amino acid ethyl esters 3-9 have been prepared by coupling ortho-ferrocenyl benzoic acid 2 to the amino acid ethyl esters of glycine, l-alanine, l-leucine, l-phenylalanine, β-alanine, 4-aminobutyric acid and (±)-2-aminobutyric acid using the conventional 1,3-dicyclohexylcarbodiimide, 1-hydroxybenzotriazole protocol. The compounds were fully characterized by a range of NMR spectroscopic techniques and by mass spectrometry (MALDI-MS, ESI-MS). The X-ray crystal structure of the l-phenylalanine derivative 6 has been determined.
Bis(ferrocenyl)mercury as a source of ferrocenyl moiety in Pd-catalyzed reactions of carbon-carbon bond formation
Beletskaya, Irina P.,Tsvetkov, Alexei V.,Latyshev, Gennadij V.,Tafeenko, Victor A.,Lukashev, Nikolai V.
, p. 653 - 663 (2007/10/03)
The application of bis(ferrocenyl)mercury as a source of ferrocenyl group in Pd-catalyzed reactions with aryl halides, acid chlorides and electrophilic alkynes has been demonstrated. The formation of dimethyl-(Z)-2,3-di(ferrocenyl)-2-butenedioate in Pd-catalyzed addition of bis(ferrocenyl)mercury to dimethylacetylenedicarboxylate has been confirmed by X-ray analysis.
