129452-86-4

Basic information

• Product Name: Benzoyl chloride, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-
• CAS NO: 129452-86-4
• Molecular Formula: C24H25ClO2Si
• Molecular Weight: 409
• Mol File: 129452-86-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-(129452-86-4)
• EPA Substance Registry System: Benzoyl chloride, 2-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-(129452-86-4)

Safety Data

• Hazardous Substances Data: 129452-86-4(Hazardous Substances Data)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 612-20-4 2-(hydroxymethyl)benzoic acid 
• 132286-87-4 (2-Bromo-benzyloxy)-tert-butyl-diphenyl-silane 
• 18982-54-2 o-bromobenzyl alcohol 
• 536743-90-5 C₄₀H₄₄O₃Si₂ 
• 132286-88-5 2-(((tert-butyldiphenylsilyl)oxy)methyl)benzoic acid 

Downstream Products

• 143294-14-8 6-N-<2-<(tert-butyldiphenylsilyl)methyl>benzoyl>-adenosine 
• 398148-63-5 2-(tert-Butyl-diphenyl-silanyloxymethyl)-N-[2-oxo-1-((2R,4S,5R)-4-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-1,2-dihydro-pyrimidin-4-yl]-benzamide 
• 143294-16-0 2-N-<2-<(tert-butyldiphenylsiloxy)methyl>benzoyl>-guanosine 
• 143294-15-9 4-N-<2-<(tert-butyldiphenylsiloxy)methyl>benzoyl>-cytidine 
• 137116-53-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-(tert-butyldimethylsilyl)-4-N-<2-<(tert-butyldiphenylsilyloxy)methyl>benzoyl>cytidine 
• 137140-40-0 5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-4-N-<2-<(tert-butyldiphenylsilyloxy)methyl>benzoyl>cytidine 
• 137116-52-0 5'-O-(4,4'-dimethoxytrityl)-3'-O-(tert-butyldimethylsilyl)-6-N-<2-<(tert-butyldiphenylsilyloxy)methyl>benzoyl>adenosine 
• 137116-58-6 5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-6-N-<2-<(tert-butyldiphenylsilyloxy)methyl>benzoyl>adenosine 
• 137140-41-1 5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-4-N-<2-<(tert-butyldiphenylsilyloxy)methyl>benzoyl>cytidinosyl 2-cyanoethyl N,N-diisopropylphosphoramidite 
• 137116-60-0 5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-6-N-<2-<(tert-butyldiphenylsilyloxy)methyl>benzoyl>adenosyl 2-cyanoethyl N,N-diisopropylphosphoramidite 
• 139052-29-2 Phosphoric acid benzotriazol-1-yl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-benzoylamino]-purin-9-yl}-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 
• 139036-69-4 Phosphoric acid benzotriazol-1-yl ester (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-benzoylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 
• 129452-92-2 Diisopropyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{2-[2-(tert-butyl-diphenyl-silanyloxymethyl)-benzoylamino]-6-oxo-1,6-dihydro-purin-9-yl}-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 
• 129452-91-1 Diisopropyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-benzoylamino]-purin-9-yl}-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 

Relevant articles and documents

ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS

Novel carboxamide substituted compounds of Formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Tyrosine Kinase 2 (Tyk2).

Efficient and low cost synthesis of the 2-(tert-butyldiphenylsilyloxymethyl)benzoyl chloride for the protection of nucleobases

The title compound was easily obtained starting from cheap phthalide in four steps with an overall yield of 67%.

Penem derivatives

Compounds of formula STR1 wherein R is hydrogen atom or C1 -C4 alkyl group optionally substituted from halogen atom or hydroxy group optionally protected, A is a Z, Z--O--C--O-- or Z--C)-- residue, wherein Z is phenylene, naphthylene