1295570-40-9Relevant academic research and scientific papers
Iron-catalyzed tandem reactions of aldehydes, terminal alkynes, and primary amines as a strategy for the synthesis of quinoline derivatives
Zhang, Yicheng,Li, Pinhua,Wang, Lei
, p. 153 - 157 (2011)
FeCl3-catalyzed three-component tandem condensation/addition/ cyclization/oxidation reactions of aldehydes, terminal alkynes, and primary amines have been developed. The processes can provide a diverse range of quinoline derivatives in good yields from simple starting materials. A possible reaction mechanism was proposed.
MOF-5 as a highly efficient and recyclable catalyst for one pot synthesis of 2,4-disubstituted quinoline derivatives
Di, Jia-Qi,Ma, Cui-Ting,Xiao, Song-Tao,Zhang, Zhan-Hui
, p. 8614 - 8620 (2020/06/09)
A MOF-5-catalyzed three-component coupling reaction was developed as an efficient approach for the synthesis of 2,4-disubstituted quinoline derivatives via a one pot three-component reaction of aromatic amines, aldehydes and alkynes with excellent yields. The easy recovery and reusability of the catalyst, broad substrate scope, short reaction time, high yields of products and solvent-free conditions make this protocol practical, environmentally friendly and economically attractive.
A Tf2O-Promoted Synthesis of Functionalized Quinolines from Ketoximes and Alkynes
Zheng, Weiping,Yang, Weiguang,Luo, Dongping,Min, Lin,Wang, Xinyan,Hu, Yuefei
supporting information, p. 1995 - 1999 (2019/03/13)
A new general synthesis of quinolines was developed from ketoximes and alkynes in the presence of Tf2O. It offered the first direct synthesis of quinolines by using the nitrilium salts generated in situ from a Tf2O-promoted Beckmann rearrangement of ketoximes under very easy conditions. (Figure presented.).
Metal free synthesis of 2,4-diarylquinoline derivatives with enamides and imines
Li, Yamin,Zhou, Xiaoqiang,Wu, Zhaoyang,Cao, Jinhui,Ma, Chaowei,He, Yongqin,Huang, Guosheng
, p. 88214 - 88217 (2015/11/09)
A metal free I2-catalyzed cyclization between enamides and imines has been developed. This approach is available for a broad range of substrates and provides an extremely simple and efficient way to construct heteroaromatic quinoline derivative
Solid-Phase Friedl?nder Synthesis Using an Alkoxyamine Linker
Yamaguchi, Kota,Noda, Takeshi,Tomizawa, Toshiki,Kanai, Eriko,Hioki, Hideaki
, p. 4990 - 4995 (2015/08/03)
A quinoline library was prepared by combinatorial synthesis using an alkoxyamine linker. Substrates were loaded onto a solid support containing an oxime linkage. After selected reactions on the solid support, the products were cleaved by a Friedl?nder-typ
