129579-54-0

Upstream product

• 1544-68-9 4-fluorophenyl isothiocyanate 
• 111279-75-5 Ethyl 1-p-fluorophenyl-2-methylthio-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 98349-24-7 ethyl 2,4,5-trifluorobenzoylacetate 
• 111279-77-7 Ethyl 1-p-fluorophenyl-2-methylsulfinyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 111279-74-4 Ethyl 3-p-fluorophenylamino-3-methylthio-2-(2,4,5-trifluoro)benzoylacrylate 

Downstream Products

• 129579-49-3 6-Fluoro-7-piperazin-1-yl-9-p-fluorophenyl-2,3,4,9-tetrahydroisothiazolo<5,4-b>quinoline-3,4-dione 
• 129579-50-6 6,7-Difluoro-9-p-fluorophenyl-2,3,4,9-tetrahydroisothiazolo<5,4-b>quinoline-3,4-dione 

Relevant academic research and scientific papers

Syntheses of 6-fluoro-7-piperazin-l-yl-9-cyclopropyl- 2,3,4,9-tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione and 6-fluoro-7-piperazin-l-yl-9-p-fluorophenyl-2,3,4,9- tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione[1]

The syntheses of 6-fluoro-7-piperazin-l-yl-9-cyclopropyl (or 9-p-fluorophenyl)-2,3,4,9- tetrahydroisothiazolo[5,4-b]quinoline-3,4-diones as well as novel synthesis of isothiazolo-3(2H)-one system are described. Key steps include the regiospecific displace