129667-10-3Relevant articles and documents
Acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions: evidence for organoaluminum intermediates
Huffman, John W.,Smith, Valerie J.,Padgett, Lea W.
, p. 2104 - 2112 (2008/09/18)
The Friedel-Crafts acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions has been reinvestigated. Evidence is presented in support of the hypothesis that when AlCl3 is used as the Lewis acid, acylation proceeds via reaction of
PREPARATION OF ALKYL-SUBSTITUTED INDOLES IN THE BENZENE PORTION. Part 3
Muratake, Hideaki,Natsume, Mitsutaka
, p. 683 - 690 (2007/10/02)
Three-step synthesis of 7- and 4-alkyl-1-tosylindoles (9 and 10) was accomplished by combination of the Friedel-Crafts acylation of 4, and the treatment of 7 and 8 with H2SO4 in 2-propanol as illustrated in Chart 2.Further a novel synthetic method of 16 was devised from 14 by way of 15.