129667-10-3 Usage
Uses
Used in Pharmaceutical Industry:
Naphthalen-1-yl(1-tosyl-1H-pyrrol-3-yl)methanone is used as a key intermediate in the synthesis of 1-alkyl-3-(1-naphthoyl)pyrroles, which represent a new class of cannabinoid compounds. These novel cannabinoids have potential therapeutic applications, particularly in the treatment of various medical conditions such as chronic pain, inflammation, and neurological disorders.
Used in Chemical Research:
Due to its unique structure and chemical properties, naphthalen-1-yl(1-tosyl-1H-pyrrol-3-yl)methanone can be utilized in chemical research for the development of new compounds with potential applications in various industries. Its ability to form meta-depside bonds and interact with biopolymers and macromolecules makes it a promising candidate for further exploration and development.
Used in Material Science:
The brown foam appearance of naphthalen-1-yl(1-tosyl-1H-pyrrol-3-yl)methanone suggests that it may have potential applications in the field of material science, particularly in the development of novel materials with specific properties. Its unique chemical structure could be exploited to create materials with enhanced properties, such as improved stability, reactivity, or selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 129667-10-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,6,6 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 129667-10:
(8*1)+(7*2)+(6*9)+(5*6)+(4*6)+(3*7)+(2*1)+(1*0)=153
153 % 10 = 3
So 129667-10-3 is a valid CAS Registry Number.
129667-10-3Relevant academic research and scientific papers
Acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions: evidence for organoaluminum intermediates
Huffman, John W.,Smith, Valerie J.,Padgett, Lea W.
, p. 2104 - 2112 (2008/09/18)
The Friedel-Crafts acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions has been reinvestigated. Evidence is presented in support of the hypothesis that when AlCl3 is used as the Lewis acid, acylation proceeds via reaction of
1-Alkyl-3-(l-naphthoyl)pyrroles: A New Class of Cannabinoid
Lainton, Julia A. H.,Huffman, John W.,Martin, Billy R.,Compton, David R.
, p. 1401 - 1404 (2007/10/02)
The design and synthesis of a series of 1-alkyl-3-(1-naphthoyl)pyrroles is described. Molecular modeling studies were employed to aid in the design of these compounds. During the course of the synthesis the Friedel-Crafts reactions of N-aryl sulfonyl pyrroles were reinvestigated. The title compounds (4) were subjected to pharmacological evaluation and the data obtained have enabled these pyrroles to be classified as cannabinoids.
PREPARATION OF ALKYL-SUBSTITUTED INDOLES IN THE BENZENE PORTION. Part 3
Muratake, Hideaki,Natsume, Mitsutaka
, p. 683 - 690 (2007/10/02)
Three-step synthesis of 7- and 4-alkyl-1-tosylindoles (9 and 10) was accomplished by combination of the Friedel-Crafts acylation of 4, and the treatment of 7 and 8 with H2SO4 in 2-propanol as illustrated in Chart 2.Further a novel synthetic method of 16 was devised from 14 by way of 15.
