129691-54-9Relevant academic research and scientific papers
Iridium-Catalyzed Carbenoid Insertion of Sulfoxonium Ylides for Synthesis of Quinoxalines and β-Keto Thioethers in Water
Xu, Yingying,Huang, Xin,Lv, Guanghui,Lai, Ruizhi,Lv, Songyang,Li, Jianglian,Hai, Li,Wu, Yong
, p. 4635 - 4638 (2020/07/04)
Sulfoxonium ylides as safe carbene precursors are described for iridium-catalyzed carbene insertions and annulation, providing a facile and green approach to access a variety of quinoxaline derivatives in water. This water-mediated method also allows the preparation of β-keto thioethers under mild condition.
Wang p-alkoxyphenylsulfoxide as a new linker and Pummerer cleavage strategy in solid-phase preparation of 1,2-diols
Rolland, Catherine,Hanquet, Gilles,Ducep, Jean-Bernard,Solladié, Guy
, p. 7563 - 7566 (2007/10/03)
para-Hydroxyphenyl-β-ketosulfide was attached to a Wang resin and oxidised to the corresponding sulfoxide with a N-protonated oxaziridinium trifluoroacetate. Reduction of the β-ketosulfoxides to the corresponding β-hydroxysulfoxides with Dibal-H was shown to be as stereoselective as in solution. Finally it was shown that the Pummerer reaction could be carried out on solid-phase and was a very efficient way to obtain diols that validates the sulfoxide group as a versatile linker for solid-phase chemistry.
