129708-76-5

Basic information

• Product Name: (6R,10R)-(+)-5,12-dibenzyl-9-oxo-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Upstream product

• 100-52-7 benzaldehyde 
• 119184-21-3 (1R,3S)-(+)-methyl 2,9-dibenzyl-3-(methoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyrido<3,4-b>indole-1-propionate 
• 129784-64-1 N¹-benzyl-(L)-tryptophan methyl ester 
• 129708-74-3 (3S)-(+)-2,9-dibenzyl-3-(methoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyrido<3,4-b>indole-1-propionic acid 
• 119184-20-2 (S)-(-)-N,N'-dibenzyltryptophan methyl ester 
• 129708-73-2 (S)-3-(1-Benzyl-1H-indol-3-yl)-2-{[1-phenyl-meth-(E)-ylidene]-amino}-propionic acid methyl ester 
• 98-88-4 benzoyl chloride 
• 119184-23-5 (6R,10R)-(+)-methyl 5,12-dibenzyl-9-oxo-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole-8-carboxylate 

Downstream Products

• 19452-84-7 (+)-taberpsychine 
• 1358-76-5 (+)-koumine 
• 119184-26-8 (6R,10R)-(+)-5-benzyl-9-oxo-12-(prop-2-ynyl)-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole 
• 129708-78-7 (E)-(2S,6R,12bR)-(+)-methyl 12-benzyl-13-methylene-18-oxo-18-methoxy-1,2,3,4,5,6,7,12,12b-octahydro-2,6-methanoindolo<2,3-a>quinolizine-3-ethylidenoate 
• 119184-30-4 (E)-(2S,6R,12bR)-(+)-methyl 12-benzyl-13-methylene-1,2,3,4,5,6,7,12,12b-octahydro-2,6-methanoindolo<2,3-a>quinolizine-3-ethylidenoate 
• 119184-31-5 (E)-(2S,6R,7aS,12aR,12bR)-(+)-methyl 12-benzyl-7a,12a-methano-13-methylene-1,2,3,4,5,6,7,7a,12,12a,12b-decahydro-2,6-methanoindolo<2,3-a>quinolizine-3-ethylidenoate 
• 129708-79-8 C₂₆H₂₆N₂O₃ 
• 129708-77-6 (6R,10R)-(+)-5-benzyl-9-<(tert-butyldimethylsilyl)oxy>-12-(prop-2-ynyl)-6,7,10,11-tetrahydro-6,10-imino-5H-cyclooctindole 
• 119184-28-0 (6R,10R)-(+)-methyl 5-benzyl-9-oxy-6,7,10,11-tetrahydro-6,10-imino-5H-cyclooctindole-12-but-2-ynoate 
• 119184-27-9 (6R,10R)-(+)-methyl 5-benzyl-9-<(tert-butyldimethylsilyl)oxy>-6,7,10,11-tetrahydro-6,10-imino-5H-cyclooctindole-12-but-2-ynoate 
• 604-99-9 (+)-koumidine 
• 604-99-9 (E)-(+)-(16S)-10-desoxysarpagine 
• 119184-29-1 (Z)-(2S,6R,12bR)-(+)-methyl 12-benzyl-13-oxo-1,2,3,4,5,6,7,12,12b-octahydro-2,6-methanoindolo<2,3-a>quinolizine-3-ethylidenoate 
• 119184-29-1 (E)-(2S,6R,12bR)-(+)-methyl 12-benzyl-13-oxo-1,2,3,4,5,6,7,12,12b-octahydro-2,6-methanoindolo<2,3-a>quinolizine-3-ethylidenoate 

Relevant articles and documents

(endo, endo)-9-Benzyl-9-azabicyclo[3.3.1]nonane-2,6-diol: An intermediate for the preparation of indole alkaloids of the macroline/sarpagine series

Two intermediates 9b and 9c already used by Cook and Magnus in their syntheses of indole alkaloids were obtained from the title compound 1 through a Fischer indolization procedure. Related tetracyclic intermediates 6 and 8 were also prepared: 6 having substituents at position 2 or 4 were directly obtained, while 8 with substituents at position 1 or 3 were selectively obtained through a convenient protection-deprotection scheme.