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[(1S,2R,3S)-3-(6-amino-9H-purin-9-yl)-2-fluorocyclopentyl]methanol is a synthetic derivative of adenosine, a naturally occurring nucleoside. It features a modified cyclopentyl ring attached to a purine base with a fluorine atom and a hydroxyl group. This chemical compound has demonstrated potential in medicinal and pharmaceutical applications, particularly in the development of new drugs targeting adenosine receptors. Its unique structure and properties make it a promising candidate for further research and development in the field of drug discovery and therapeutics.

129746-12-9

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129746-12-9 Usage

Uses

Used in Pharmaceutical Industry:
[(1S,2R,3S)-3-(6-amino-9H-purin-9-yl)-2-fluorocyclopentyl]methanol is used as a key compound for the development of new drugs targeting adenosine receptors. Its unique structure allows for potential applications in the treatment of various conditions, such as cardiovascular diseases, neurological disorders, and cancer, by modulating the activity of adenosine receptors.
Used in Drug Discovery:
In the field of drug discovery, [(1S,2R,3S)-3-(6-amino-9H-purin-9-yl)-2-fluorocyclopentyl]methanol serves as a valuable starting point for the design and synthesis of novel adenosine receptor modulators. Its structural features can be further optimized to enhance the potency, selectivity, and pharmacokinetic properties of the resulting drug candidates.
Used in Therapeutics:
[(1S,2R,3S)-3-(6-amino-9H-purin-9-yl)-2-fluorocyclopentyl]methanol has potential therapeutic applications due to its interaction with adenosine receptors. By modulating the activity of these receptors, it may contribute to the development of new treatments for a range of diseases, including those affecting the cardiovascular, central nervous, and immune systems.

Check Digit Verification of cas no

The CAS Registry Mumber 129746-12-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,4 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 129746-12:
(8*1)+(7*2)+(6*9)+(5*7)+(4*4)+(3*6)+(2*1)+(1*2)=149
149 % 10 = 9
So 129746-12-9 is a valid CAS Registry Number.

129746-12-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(1S,2R,3S)-3-(6-aminopurin-9-yl)-2-fluorocyclopentyl]methanol

1.2 Other means of identification

Product number -
Other names 6'-F-carbocyclicddA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129746-12-9 SDS

129746-12-9Downstream Products

129746-12-9Relevant academic research and scientific papers

Synthesis of Compounds active against HIV. Part 2. Preparation of some 2',3'-Dideoxy-6'-fluorocarbocyclic Nucleosides

Coe, Diane M.,Myers, Peter L.,Parry, David M.,Roberts, Stanley M.,Storer, Richard

, p. 151 - 153 (2007/10/02)

A series of 2',3'-dideoxy-6'-fluorocarbocyclic nucleosides have been prepared and tested for activity against HIV; compound (20) showed weak antiviral activity.

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