129758-71-0Relevant academic research and scientific papers
An environmentally friendly procedure for Mukaiyama aldol and Mukaiyama-Michael reactions using a catalytic amount of DBU under solvent- and metal-free conditions
Shen, Zhi-Liang,Ji, Shun-Jun,Loh, Teck-Peng
, p. 507 - 508 (2007/10/03)
Mukaiyama aldol and Mukaiyama-Michael reactions can proceed smoothly in the presence of a catalytic amount of DBU (20% mmol), to afford the corresponding products in moderate to good yields. This solvent- and metal-free approach provides an environmentall
New one carbon homologation reagents utilizing electrochemical oxidation of organosilicon compounds
Yoshida,Matsunaga,Murata,Isoe
, p. 615 - 624 (2007/10/02)
Phenylthio(trimethylsilyl)methane, phenylthiobis(trimethylsilyl)methane, methoxy(trimethylsilyl)-methane, and methoxybis(trimethylsilyl)methane are deprotonated and the resulting anions are alkylated with electrophiles such as organic halides. The alkylation products are readily converted into the corresponding dimethyl acetals or methyl esters by electrochemical oxidation in methanol.
An Efficient Method for the Direct Peroxygenation of Various Olefinic Compounds with Molecular Oxygen and Triethylsilane Catalyzed by a Cobalt(II) Complex
Isayama, Shigeru
, p. 1305 - 1310 (2007/10/02)
An efficient method for the direct peroxygenation of various olefinic compounds with molecular oxygen and triethylsilane (Et3SiH) was developed by the use of a catalytic amount of a bis(1,3-diketonato)cobalt(II) complex.According to the above method, 1-phenyl-3-triethylsilyldioxybutane (2) was directly produced from 4-phenyl-1-butene (1) by means of a reaction with O2 and Et3SiH at room temperature.Styrene (3) and ethyl acrylate (5a) were also smoothly peroxygenated to give 1-phenyl-1-triethylsilyldioxyethane (4) and ethyl 2-triethylsilyldioxypropionate (6a) by using a small amount of t-BuOOH as an initiator.The successive desilylation of 6a and reduction of the resulting ethyl 2-hydroperoxypropionate (8a) afforded the corresponding alcohol, ethyl lactate (10a), in a high yield.The synthetic utility of the present peroxygenation reaction was demonstrated in the preparation of α-hydroxy esters 10a-e from several α,β-unsaturated esters 5a-e via the corresponding triethylsilyldioxy derivatives.
METHOXY(TRIMETHYLSILYL)METHANE AND METHOXYBIS(TRIMETHYLSILYL)METHANE AS NEW REAGENTS FOR HOMOLOGATION
Yoshida, Jun-ichi,Matsunaga, Shin-ichiro,Isoe, Sachihiko
, p. 219 - 222 (2007/10/02)
New synthons of formyl anion methoxy(trimethylsilyl)methane (1)) and alkoxycarbonyl anion (methoxybis(trimethylsilyl)methane (2)) have been developed using oxidative cleavage of the carbon-silicon bond by anodic oxidation.
