129790-04-1

Upstream product

• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 591-19-5 m-Bromoaniline 

Downstream Products

• 185316-44-3 7-bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one 
• 158326-77-3 4,4-dimethyl-7-bromo-1,2,3,4-tetrahydroquinoline 
• 144583-87-9 N-propyl-N-(3-bromophenyl)-3,3-dimethyl-acrylamide 

Relevant academic research and scientific papers

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential

Signal transducers and activators of transcription 5A and 5B (STAT5A and STAT5B) are two closely related STAT family members that are crucial downstream effectors of tyrosine kinase oncoproteins such as FLT3-ITD in acute myeloid leukemia (AML) and BCR-ABL

N-aryl substituted tetrahydroquinolines having retinoid agonist, retinoid antagonist or retinoid inverse agonist type biological activity

Compounds of the formula STR1 where the symbols have the meaning defined in the specification, have retinoid, retinoid antagonist or retinoid inverse agonist-like biological activity.

Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-thio-1,2,3,4-tetrahdroquinolinyl, 2-alkylthio-3,4-dihydroquinolinyl or 2-alkoxy-3,4-dihydroquinolinyl group having retinoid-like biological activity

Compounds of the formula STR1 where the symbols are defined as in the specification.