185316-44-3

Usage

Uses

Used in Pharmaceutical Research:
7-Bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one is used as a research compound for its anti-inflammatory and anti-cancer properties. Its unique molecular structure allows for the development of new drugs targeting various medical conditions.
Used in Organic Synthesis:
7-Bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one is used as a key intermediate in the synthesis of other organic compounds, particularly those with potential pharmaceutical applications.
Used in Drug Development:
Due to its biological activities and unique molecular structure, 7-bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one is used as a starting material in the development of new drugs for various medical conditions, including cancer and inflammatory disorders.
Used in Medicinal Chemistry:
7-Bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one serves as a valuable compound in medicinal chemistry, where it can be modified and optimized to enhance its therapeutic potential and selectivity for specific targets.

Upstream product

• 129790-04-1 N-(3-bromophenyl)-3,3-dimethyl-acrylamide 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 591-19-5 m-Bromoaniline 

Downstream Products

• 185316-31-8 ethyl 4-[(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-1-isopropyl-7-quinolinyl)ethynyl]benzoate 
• 198696-11-6 4-(1-Isopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-ylethynyl)-benzoic acid ethyl ester 
• 185316-27-2 ethyl 4-[(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-7-quinolinyl)ethynyl]benzoate 
• 198696-09-2 4-(4,4-Dimethyl-1,2,3,4-tetrahydro-quinolin-7-ylethynyl)-benzoic acid ethyl ester 
• 158326-77-3 4,4-dimethyl-7-bromo-1,2,3,4-tetrahydroquinoline 

Relevant academic research and scientific papers

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential

Signal transducers and activators of transcription 5A and 5B (STAT5A and STAT5B) are two closely related STAT family members that are crucial downstream effectors of tyrosine kinase oncoproteins such as FLT3-ITD in acute myeloid leukemia (AML) and BCR-ABL

Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-thio-1,2,3,4-tetrahdroquinolinyl, 2-alkylthio-3,4-dihydroquinolinyl or 2-alkoxy-3,4-dihydroquinolinyl group having retinoid-like biological activity

Compounds of the formula STR1 where the symbols are defined as in the specification.