1298101-47-9

Basic information

• Product Name: tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate
• Synonyms: tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate;(1s,3r)-3-amino-1-(boc-amino)cyclohexane;tert-butyl N-[(1S,3R)-3-aminocyclohexyl]carbamate
• CAS NO: 1298101-47-9
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.30458
• Mol File: 1298101-47-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate(1298101-47-9)
• EPA Substance Registry System: tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate(1298101-47-9)

Safety Data

• Hazardous Substances Data: 1298101-47-9(Hazardous Substances Data)

Usage

General Description

Tert-butyl (1S,3R)-3-aminocyclohexylcarbamate is a chemical compound with the molecular formula C11H23N2O2. It is a derivative of tert-butyl carbamate and contains an aminocyclohexyl group. tert-butyl (1S,3R)-3-aMinocyclohexylcarbaMate is used in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and functional groups make it a versatile and valuable reagent for the preparation of diverse molecular scaffolds and pharmacologically relevant molecules. Its properties and potential applications make it an important target for research and development in the field of organic and medicinal chemistry.

Upstream product

• 53084-60-9 ethyl (1R,3S)-3-aminocyclohexanecarboxylate 
• 227783-08-6 (1S,3R)-3-ethoxycarbonylcyclohexane-1-carboxylic acid 
• 1261225-49-3 [3-(1R,3S)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester 
• 1259278-09-5 ethyl (1R,3S)-3-benzyloxycarbonylaminocyclohexane-1-carboxylate 
• 1259278-11-9 benzyl N-[(1S,3R)-3-carbamoylcyclohexyl]carbamate 
• 1259278-12-0 benzyl N-[(1S,3R)-3-aminocyclohexyl]carbamate 
• 218772-92-0 (±)-cis-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylic acid 
• 1261225-48-2 [3-(1S,3R)-benzyloxycarbonylaminocyclohexyl]-1-carbamic acid tertbutyl ester 
• 222530-39-4 (1R,3S)-3-(tert-butoxycarbonylamino)aminocyclohexanecarboxylic acid 

Relevant articles and documents

BCAT MODULATION

This disclosure relates to, in part, the treatment of an organic acidemia in a subject in need thereof via administration of a therapeutically effective amount of compounds that inhibit BCAT2. The disclosure also relates to, in part, methods for identifying a candidate compound for treatment of organic acidemias.

HETEROCYCLIC INDOLES FOR USE IN INFLUENZA VIRUS INFECTION

The current invention relates to a compound of formula (I) which can be used for the treatment of, or against viral influenza infections.

POLYCYCLIC INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7)

The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, lymphoma, melanoma, multiple myeloma, breast cancer, Ewing' s sarcoma, osteosarcoma, brain cancer, neuroblastoma, lung cancer), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 7 (CDK7), cyclin-dependent kinase 12 (CDK12), or cyclin-dependent kinase 13 (CDK13)), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.