1300031-62-2Relevant articles and documents
METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE
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Paragraph 00616; 00754; 00755; 00756, (2021/08/13)
The present disclosure relates to compounds and methods for modulating the expression of dmpk, and treating diseases and conditions in which dmpk plays an active role. The compound can be a transcription modulator molecule having a first terminus, a second terminus, and oligomeric backbone, wherein: a) the first terminus comprises a DNA-binding moiety capable of noncovalently binding to a nucleotide repeat sequence CAG or CTG; b) the second terminus comprises a protein-binding moiety binding to a regulatory molecule that modulates an expression of a gene comprising the nucleotide repeat sequence CAG or CTG; and c) the oligomeric backbone comprising a linker between the first terminus and the second terminus.
7-(3,5-Dimethyl-4-Isoxazolyl)-8-(Methyloxy)-1H-Imidazo[4,5-C]Quinoline Derivatives
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Paragraph 0178-0179, (2014/03/21)
Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
NOVEL COMPOUNDS
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Page/Page column 30-31, (2012/11/07)
Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.