10558-25-5

Usage

Uses

Used in Chemical Synthesis:
4-Bromo-3,5-dimethylisoxazole is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows it to be a valuable building block in the synthesis of more complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Bromo-3,5-dimethylisoxazole is used as a key component in the synthesis of specific pharmaceuticals. Its presence in the molecular structure can contribute to the overall activity and efficacy of the final drug product.
Used in the Preparation of (tert-butyldimethylsilyl)-(3,5-dimethylisoxazol-4-yl)phenylamine:
4-Bromo-3,5-dimethylisoxazole is used as a starting material for the preparation of (tert-butyldimethylsilyl)-(3,5-dimethylisoxazol-4-yl)phenylamine, a compound that may have potential applications in various fields, such as materials science or pharmaceuticals.
Used in the Preparation of 3,3′,5,5′-tetramethyl-4,4′-diisoxazole:
Additionally, 4-Bromo-3,5-dimethylisoxazole is utilized in the synthesis of 3,3′,5,5′-tetramethyl-4,4′-diisoxazole, which could be relevant in the development of new materials or chemicals with specific properties.

InChI:InChI=1/C5H6BrNO/c1-3-5(6)4(2)8-7-3/h1-2H3

Upstream product

• 300-87-8 3,5-dimethyl-1,2-oxazole 

Downstream Products

• 1044822-29-8 methyl 5-bromo-4,6-dimethyl-2-phenyl-2H-1,3-oxazine-2-carboxylate 
• 1195901-24-6 (tert-butyl-dimethyl-silanyl)-(3,5-dimethyl-isoxazol-4-yl)-phenyl-amine 
• 59184-12-2 4-mesityl-3,5-dimethylisoxazole 
• 1265614-72-9 (3,5-dimethylisoxazol-4-yl)[4-(1H-1,2,4-triazol-1-yl)phenyl]methanol 
• 832114-00-8 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole 
• 387353-84-6 3,5-dimethyl-4-dimethylphenylsilylisoxazole 
• 4345-46-4 3,5-dimethyl-4-phenyl-isoxazole 
• 154822-66-9 3,5-dimethyl-4-[4-(methyloxy)phenyl]isoxazole 
• 1268486-66-3 N-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzyl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide 
• 1616100-60-7 tert-butyl ((2S,4R)-2-(5-bromo-2,4-difluorophenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-hydroxybutan-2-yl)carbamate 
• 1300031-61-1 [3-(3,5-dimethyl-4-isoxazolyl)-4-(methyloxy)phenyl]amine 
• 1300031-62-2 3,5-dimethyl-4-[2-(methyloxy)-5-nitrophenyl]isoxazole 
• 1453841-36-5 3,5-dimethyl-4-(2-methylquinolin-6-yl)isoxazole 
• 1395283-74-5 4-(3,5-difluorophenyl)-3,5-dimethylisoxazole 

Relevant academic research and scientific papers

Orthogonal Stability and Reactivity of Aryl Germanes Enables Rapid and Selective (Multi)Halogenations

While halogenation is of key importance in synthesis and radioimaging, the currently available repertoire is largely designed to introduce a single halogen per molecule. This report makes the selective introduction of several different halogens accessible. Showcased here is the privileged stability of nontoxic aryl germanes under harsh fluorination conditions (that allow selective fluorination in their presence), while displaying superior reactivity and functional-group tolerance in electrophilic iodinations and brominations, outcompeting silanes or boronic esters under rapid and additive-free conditions. Mechanistic experiments and computational studies suggest a concerted electrophilic aromatic substitution as the underlying mechanism.

AGONISTS OF GPR40

The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are there-fore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.