13003-74-2

Upstream product

• 17290-70-9 isosinensetin 
• 71847-58-0 5,8-dihydroxy-7-methoxy-2-(3,4-dimethoxyphenyl)-4-benzopyrone 
• 77-78-1 dimethyl sulfate 
• 114021-60-2 2'-hydroxy-3,4,4',6'-tetramethoxychalcone 
• 76650-20-9 1-(2,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)propenone 
• 29080-58-8 5-hydroxy-3',4',7-trimethoxyflavone 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 114866-06-7 2'-(3,4-dimethoxybenzoyloxy)-3',4',6'-trimethoxyacetophenone 
• 114866-05-6 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-1,3-propanedione 
• 7507-98-4 1-(2-hydroxy-3,4,6-trimethoxyphenyl)ethanone 
• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 18003-33-3 3',4',5,6,7-pentahydroxyflavone 

Relevant academic research and scientific papers

Regioselective hydroxylation of 2-hydroxychalcones by dimethyldioxirane towards polymethoxylated flavonoids

The flavone nucleus is part of a large number of natural products and medicinal compounds. In this presentation the novel regioselective hydroxylation of hydroxyarenes with DMD is described. The results showed further that flavonoids with 5-hydroxy group were selectively oxyfunctionalized at the para-position C8 carbon atom by DMD. Finally, according to this methodology, the naturally occurring isosinensetin, tangeretin, sinensetin, nobiletin, natsudaidain, gardenin B, 3,3′,4′,5,6,7,8- heptamethoxyflavone, quercetin and its derivatives were synthesized.

Syntheses of 6-Hydroxyluteolin and Sinensetin by Wessely - Moser Rearrangement

Syntheses of 6-hydroxyluteolin (1) and sinensetin (2) are described.The compounds 6 and 7 afford 1 on Wessely - Moser rearrangement.The synthetic samples 1 and 2 are identical (m.m.p. and co-ir) with the authentic samples.