130073-07-3

Basic information

• Product Name: 1,1-bis-(2-methoxyphenyl)ethanol
• Synonyms: 1,1-bis-(2-methoxyphenyl)ethanol
• CAS NO: 130073-07-3
• Molecular Weight: 258.317
• Mol File: 130073-07-3.mol

Chemical Properties

• CAS DataBase Reference: 1,1-bis-(2-methoxyphenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-bis-(2-methoxyphenyl)ethanol(130073-07-3)
• EPA Substance Registry System: 1,1-bis-(2-methoxyphenyl)ethanol(130073-07-3)

Safety Data

• Hazardous Substances Data: 130073-07-3(Hazardous Substances Data)

Upstream product

• 13102-33-5 2,2'-dimethoxybenzophenone 
• 75-16-1 methylmagnesium bromide 
• 591-87-7 Allyl acetate 
• 16750-63-3 2-methoxyphenylmagnesium bromide 

Downstream Products

• 87804-18-0 1,1-Bis(2-hydroxyphenyl)ethane 
• 5293-93-6 β,β-bis(o-methoxyphenyl)vinyl bromide 
• 33451-17-1 1,1-bis-(2-methoxy-phenyl)-ethane 
• 5293-78-7 2,2'-dimethoxytolane 
• 14310-34-0 1,2-bis(2-methoxyphenyl)ethane 
• 28358-60-3 1-methoxy-2-[1-(2-methoxyphenyl)ethenyl]benzene 

Relevant articles and documents

Access to Enantiopure Triarylmethanes and 1,1-Diarylalkanes by NHC-Catalyzed Acylative Desymmetrization

We present herein an unprecedented, efficient and enantioselective synthesis of triarylmethanes and 1,1-diarylalkanes through N-heterocyclic carbene-catalyzed acylative desymmetrization of bisphenols. This method utilizes readily available substrates, reagents and a simple procedure to deliver the valuable products in excellent enantiopurity. DFT calculations reveal that the selectivity is governed by the C?C bond cleavage step of the tetrahedral intermediate leading to the ester product. A transition state model featuring a combination of intramolecular hydrogen bond and steric effect is developed to explain the enantioselectivity.

Practical iron-catalyzed allylations of aryl grignard reagents

An operationally simple iron-catalyzed reductive cross-coupling reaction between aryl halides and allyl electrophiles has been developed. The underlying domino process exhibits high versatility with respect to the allylic leaving group (acetate, tosylate, diethyl phosphate, methyl carbonate, trimethylsilanolate, methanethiolate, chloride, bromide) and high economic and environmental sustainability with respect to the catalyst system (0.2-5 mol% tris(acetylacetonato)iron(III), ligand-free) and reaction conditions (tetrahydrofuran, 0°C, 45 min).

Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids

Dibenzo[d,g][1,3]dioxocin-6-carboxylic acids substituted by methyl or ethyl or a moiety --CH2 CH2 -- at the 12-position and optionally substituted at other positions, such as methyl 4'-chlorospiro(cyclopropane-1,12'(12'H)-dibenzo[d,g][1,3]dioxocin)-6'-carboxylic acid, and their agriculturally acceptable esters, amides, and salts are useful for the control of undesirable vegetation. The 1,1-diarylcyclopropane intermediates required for the spirocyclopropane compounds can be prepared from appropriately substituted 1,1-diarylethene procursors by reaction with phenylthiomethyl lithium reagent.