130087-68-2Relevant academic research and scientific papers
SYNTHESIS OF FUNGITOXIC 1,2,4-TRIAZOLOTHIAZIN-5-ONES INVOLVING RING TRANSFORMATION OF MICHAEL ADDUCTS OF 4-BENZYLIDENE-5-OXAZOLONES AND 3-MERCAPTO-1,2,4-TRIAZOLES
Yadav, Lal Dhar Singh,Shukla, Kripa Nath,Singh, Harendra
, p. 861 - 868 (2007/10/02)
Michael type addition of 3-mercapto-1,2,4-triazoles (Ia-d) to 4-benzylidene-5-oxazolones (IIa-c) followed by ring transformation of the resulting adducts (IIIa-l) furnished 6,7-dihydro-3-aryl/aryloxymethyl-6-benzamido-7-aryl-5H-1,2,4-triazolothiazin-5-ones (IVa-l), in one vessel.The products IVa-l were compared with Dithane M-45, a commercial fungicide, for their fungitoxicity against Aspergillus niger and Fusarium oxysporium, and the results have been correlated with the structural features of the tested compounds.
