13014-24-9

Usage

General Description

Slightly opaque pale yellow liquid.

Air & Water Reactions

3,4-Dichlorobenzotrichloride may be sensitive to moisture. Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as 3,4-Dichlorobenzotrichloride, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

SYMPTOMS: Symptoms of exposure to 3,4-Dichlorobenzotrichloride may include skin and eye irritation.

Fire Hazard

3,4-Dichlorobenzotrichloride is probably combustible.

Upstream product

• 553-94-6 4-bromo-m-xylene 
• 27260-64-6 4-chloro-1,3-bis-(trichloromethyl)-benzene 
• 10388-10-0 2-chloro-1,4-bis-(trichloromethyl)-benzene 
• 5216-25-1 4-chlorotrichloromethylbenzene 
• 95-50-1 1,2-dichloro-benzene 
• 95-75-0 3,4-Dichlorotoluene 

Downstream Products

• 328-84-7 1,2-dichloro-4-(trifluoromethyl)benzene 
• 7647-01-0 hydrogenchloride 
• 56148-83-5 2,4,5-trichloro-1-(trifluoromethyl)benzene 
• 50594-82-6 1-trifluoromethyl-3,4,5-trichlorobenzene 
• 97985-54-1 2,3,4,5-tetrachloro-1-(trifluoromethyl)benzene 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 7506-97-0 3,4-dichloro-N,N-diethylbenzamide 
• 6574-99-8 3,4-dichloro-benzonitrile 
• 3024-72-4 3,4-dichlorobenzoyl chloride 

Relevant academic research and scientific papers

Novel 3, 4, 5- preparation method of methyltrifluorobenzotrifluoride (by machine translation)

Compared with the prior art, the 3, 4, 5 - method disclosed by the invention disclosed. by 3,4 - the invention has the, advantages that, a, large, number of 3, 4, 5 - the raw materials. used in the present, invention avoids the pollution to the environment, the, environmental hazard is reduced, the production cost of, the target compound is, reduced, the economic benefit is; improved, the, yield of, the product is high, and the, operation is simple; and convenient . (by machine translation)

Novel process for synthesizing 3,4-dichlorobenzotrifluoride

The invention discloses a novel process for synthesizing 3,4-dichlorobenzotrifluoride, wherein the target compound is obtained by using 3,4-dichlorotoluene as a raw material and using a mixture of cuprous chloride and copper powder as a catalyst through a two-step reaction of chlorination and fluorination. Compared with the method in the prior art, the method of the invention has the following characteristics that the chlorination side reaction is less, the product purity is high, the 3,4-dichlorobenzotrifluorideis produced by using the byproduct 3,4-dichlorotoluene as the raw material so as to achieve the advantages of wide raw material source, low price, turning of byproduct into treasure and target compound production cost reducing, and the catalyst has characteristics of low price andconvenient recovery so as to reduce the production cost of the target compound, increase the economic benefit and avoid environmental pollution.

Ionic Liquids Catalyzed Friedel–Crafts Alkylation of Substituted Benzenes with CCl4 Toward Trichloromethylarenes

Abstract: An ionic liquid catalyzed Friedel–Crafts alkylation reaction of substituted benzenes with CCl4 was developed. The reaction proceeded efficiently under mild conditions, gave corresponding trichloromethylarenes with diversity functional groups in moderate to good yields. The influence of Lewis acidity of ionic liquids on the conversion of the alkylation reaction has been investigated. Notably, the probable mechanism of this reaction has been proposed with the assistance of 27Al NMR spectroscopy. It was noteworthy that the predominance of [Al2Cl7]? species in EmimCl–AlCl3, N = 0.67 could be detected by 27Al NMR spectral analysis, and [AlCl4]? was generated at the beginning of reaction. Additionally, it was found that [AlCl4]? could be transformed into [Al2Cl7]? when the reaction finished. Some control experiments confirmed that the interaction between Lewis acidic species [Al2Cl7]? of the ionic liquid and CCl4 led to the change in speciation of aluminum during the alkylation reactions. Graphical Abstract: [Figure not available: see fulltext.].

Method for preparing 3,4-dichlorobenzonitrile

The invention discloses a method for preparing 3,4-dichlorobenzonitrile. 3,4-Dichlorotoluene is taken as a raw material, benzoyl peroxide is added at 80-110 DEG C, chlorine gas is introduced for a reaction, when the content of the 3,4-dichlorotoluene is less than or equal to 0.03%, the reaction is stopped, 3,4-dichlorobenzotrichloride is prepared, then in the presence of a catalyst, the 3,4-dichlorobenzotrichloride and ammonium chloride react at 170-230 DEG C, when the content of the 3,4-dichlorobenzotrichloride is less than 0.05%, the reaction is stopped, the product is subjected to reduced pressure distillation, and the pure 3,4-dichlorobenzonitrile product is obtained. The method has the advantages that the reaction conditions are mild, the control is easy, the yield is high, no side reaction exists, environmental friendliness is achieved, the cost of reaction raw materials is low, hydrogen chloride gas produced by the reaction can be collected as a by-product hydrochloric acid, andeconomic benefits are increased.

Efficient chlorination process of 3,4-dichlorobenzotrifluoride

The invention discloses an efficient chlorination process of 3,4-dichlorobenzotrifluoride, and belongs to the field of organic synthesis. According to the method, 3,4-dichlorotoluene is used as a rawmaterial, a mixture catalyst of cuprous chloride and copper powder is added, a target compound is obtained through two-step reaction of chlorination and fluorination, the raw materials applied in thereaction process are convenient to purchase, the production cost is low, after-treatment is simple, reaction conditions are mild, and good economic benefits and social benefits are achieved.

Efficient chlorination process of dichlorobenzotrifluoride

The invention discloses an efficient chlorination process of dichlorobenzotrifluoride, and belongs to the field of organic synthesis. According to the method, dichlorotoluene is used as a raw material, a mixture catalyst of cuprous chloride and copper powder is added, a target compound is obtained through two-step reaction of chlorination and fluorination, the raw materials applied in the reactionprocess are convenient to purchase, the production cost is low, after-treatment is simple, reaction conditions are mild, and good economic benefits and social benefits are achieved.

Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel

Process for the production of 4-amino-3,5-dichlorobenzotrifluoride comprising the stages:A) chlorination of 4-chlorobenzotrichloride, in the presence of a Lewis acid, in order to obtain a mixture of 3,4-dichlorobenzotrichloride and 3,4,5-trichlorobenzotrichloride and other chlorine derivatives by performing the reaction in such a manner as to obtain in the mixture of reaction products a quantity of 3,4,5-trichlorobenzotrichloride of greater than 10% by weight and preferably of between 20% and 30% by weight and a concentration of 3,4-trichlorobenzotrichloride of less than 90% by weight and preferably of between approx. 55% and 75% by weight, relative to the total weight of the chlorinated derivatives;B) fluorination with hydrofluoric acid of the mixture of chlorination products as obtained in stage A) in order to obtain the corresponding benzotrifluorides; andC) separation by distillation of the mixture of products of stage B) in order to obtain 3,4,5-trichlorobenzotrifluoride or an isomeric mixture of 3,4,5- and 2,4,5-trichlorobenzotrifluoride; andD) amination of 3,4,5-trichlorobenzotrifluoride or of said isomeric mixture.

Process for the preparation of certain nuclear chlorinated benzotrichlorides

A process for the preparation of 3,4-dichlorobenzotrichloride, 3,4,5-trichlorobenzotrichloride, 2,4,5-trichlorobenzotrichloride or 2,3,4,5-tetrachlorobenzotrichloride which comprises contacting p-chlorobenzotrichloride of the formula STR1 with chlorine or an agent which releases chlorine at a temperature between 0° C. and 180° C. in the presence of an iron (III) chloride or aluminum chloride catalyst or a mixture of iron (III) chloride or aluminum chloride with sulfur dichloride or disulfur dichloride.