130145-46-9Relevant academic research and scientific papers
Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents
Kumar, Kunal,Awasthi, Divya,Lee, Seung-Yub,Zanardi, Ilaria,Ruzsicska, Bela,Knudson, Susan,Tonge, Peter J.,Slayden, Richard A.,Ojima, Iwao
, p. 374 - 381 (2011/03/18)
Libraries of novel trisubstituted benzimidazoles were created through rational drug design. A good number of these benzimidazoles exhibited promising MIC values in the range of 0.5-6 μg/mL (2-15 μM) for their antibacterial activity against Mtb H37Rv strai
BENZIMIDAZOLES AND PHARMACEUTICAL COMPOSITIONS THEREOF
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Page/Page column 19-20, (2008/12/08)
The present invention relates to novel benzimidazole derivatives and pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating a patient infected by Mycobacterium tuberculosis or Francisella tulerensis by ad
Potential Antimitotic Agents. Synthesis of Some Ethyl Benzopyrazin-7-ylcarbamates, Ethyl Pyridopyrazin-7-ylcarbamates, and Ethyl Pyrido-as-triazin-7-ylcarbamates
Temple, Carroll,Rener, Gregory A.
, p. 3044 - 3050 (2007/10/02)
Ring analogues and derivatives of the 1,2-dihydropyridopyrazin-7-ylcarbamates (e.g., 29), antimitotic agents with antitumor activity, were prepared in the search for compounds with greater selectivity.Methods were developed for the conversion of su
