130147-42-1Relevant articles and documents
Improved routes for the preparation of pentaerythritol mono-O-benzyl ether
Al-Mughaid, Hussein,Grindley, T. Bruce
, p. 2569 - 2575 (2006)
Two new efficient routes for the synthesis of pentaerythritol monobenzyl ether are described. In one route, the known mono-O-benzylidenepentaerythritol (5) is selectively benzylated via its dibutylstannylene acetal and then the benzylidene acetal is hydro
RAPAMYCIN ANALOGS AND USES THEREOF
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, (2020/01/08)
The present invention provides compounds, compositions thereof, and methods of using the same.
Development of Tetramethylenedisulfotetramine (TETS) Hapten Library: Synthesis, Electrophysiological Studies, and Immune Response in Rabbits.
Barnych, Bogdan,Vasylieva, Natalia,Joseph, Tom,Hulsizer, Susan,Nguyen, Hai M.,Cajka, Tomas,Pessah, Isaac,Wulff, Heike,Gee, Shirley J.,Hammock, Bruce D.
, p. 8466 - 8472 (2017/06/28)
There is a need for fast detection methods for the banned rodenticide tetramethylenedisulfotetramine (TETS), a highly potent blocker of the γ-aminobutyric acid (GABAA) receptors. General synthetic approach toward two groups of analogues was dev
A new having glucoskeleton threotol Pentaphenol alkylalkoxysilane compd. contg., using the same and its intermediate surface modifying agent
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, (2018/10/16)
PROBLEM TO BE SOLVED: To provide a novel surface modifier having high solubility to various organic solvents and excellent water repellency and oil repellency without containing a long-chain perfluoroalkyl group which is a problem in terms of environment and to provide an intermediate thereof.SOLUTION: There are provided a compound intermediate represented by the following general formula (1): [HCFCFOCH]C[CHOH](1) (where m is 2 or 3 and n is an integer satisfying 4-m), a fluorine-containing alkoxysilane compound represented by the following general formula (2): [HCFCFOCH]C[CH-X-Y-Si(OR)](2) (where m and n are the same as in general formula (1); X is a linking group representing an intermolecular interaction; Y is an alkylene group having 1 to 12 carbon atoms; and Ris an alkyl group having 1 to 6 carbon atoms) which is derived from the intermediate; and a surface modifier containing the fluorine-containing alkoxysilane compound as a constituent component.
COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION
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Page/Page column 179-180, (2015/11/23)
The present embodiments provide methods, compounds, and compositions for treating, preventing, ameliorating a disease associated with excess growth hormone using antisense compounds oligonucleotides targeted to growth hormone receptor (GHR).
COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION
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Page/Page column 189, (2015/11/23)
The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with dysregulation of the complement alternative pathway by administering a Complement Factor B (CFB) specific inhibitor to a subject.
COMPOSITIONS AND METHODS FOR MODULATING ANGIOPOIETIN-LIKE 3 EXPRESSION
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Page/Page column 211, (2015/11/23)
Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing lipids and/or glucose in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease and/or metabolic disease, or a symptom thereof, in an individual in need thereof.
CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE
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, (2014/11/13)
Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
A structured monodisperse PEG for the effective suppression of protein aggregation
Muraoka, Takahiro,Adachi, Kota,Ui, Mihoko,Kawasaki, Shunichi,Sadhukhan, Nabanita,Obara, Haruki,Tochio, Hidehito,Shirakawa, Masahiro,Kinbara, Kazushi
, p. 2430 - 2434 (2013/04/23)
Part of the solution: A PEG with a discrete triangular structure exhibits hydrophilicity/hydrophobicity switching upon increasing temperatures, and suppresses the thermal aggregation of lysozyme to retain nearly 80 % of the enzymatic activity. CD and NMR
The design and synthesis of highly branched and spherically symmetric fluorinated oils and amphiles
Jiang, Zhong-Xing,Yu, Y. Bruce
, p. 3982 - 3988 (2007/10/03)
A new surfactant design principle, based on concepts borrowed from protein science, is proposed. Using this principle, a class of highly branched and spherically symmetric fluorinated oils and amphiles has been designed and synthesized, for potential appl
