632293-73-3

Upstream product

• 115-77-5 Pentaerythritol 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 130147-42-1 2-<(benzyloxy)methyl>-2-(hydroxymethyl)-1,3-propanediol 
• 99231-99-9 4-<(benzyloxy)methyl>-1-methyl-2,6,7-trioxabicyclo<2.2.2>octane 
• 19309-39-8 1-methyl-4-(hydroxymethyl)-2,6,7-trioxabicyclo-[2.2.2]-octane 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION

The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with dysregulation of the complement alternative pathway by administering a Complement Factor B (CFB) specific inhibitor to a subject.

COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION

The present embodiments provide methods, compounds, and compositions for treating, preventing, ameliorating a disease associated with excess growth hormone using antisense compounds oligonucleotides targeted to growth hormone receptor (GHR).

CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE

Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.

NEW PHOSPHORAMIDITE COMPOUNDS

Novel phosphoramidites having various functional groups can be advantageously used as new building blocks to synthesize various oligodeoxyribonucleotides which are useful for the development of a highly efficient diagnostic agent and the synthesis of new

Synthesis of Novel Phosphoramidite Building Blocks from Pentaerythritol

The synthesis of four types of phosphoramidites containing various protecting groups (DMTr, TBDMS, Lev) has been achieved starting from pentaerythritol. The protecting groups can be deprotected selectively in an orthogonal manner.