130155-33-8

Usage

Uses

Used in Pharmaceutical Applications:
(3β,22E)-ergosta-5,7,22-trien-3-yl D-glucopyranoside is used as a potential therapeutic agent for its anti-inflammatory properties, helping to reduce inflammation and alleviate symptoms associated with various inflammatory conditions.
(3β,22E)-ergosta-5,7,22-trien-3-yl D-glucopyranoside is used as an anticancer agent, targeting cancer cells and potentially inhibiting their growth and proliferation, offering a novel approach to cancer treatment.
(3β,22E)-ergosta-5,7,22-trien-3-yl D-glucopyranoside is used as a cholesterol-lowering agent, potentially aiding in the management of hypercholesterolemia and reducing the risk of cardiovascular diseases.
Used in Environmental Science:
(3β,22E)-ergosta-5,7,22-trien-3-yl D-glucopyranoside is used as a biomarker for fungal biomass in environmental samples, facilitating the assessment of fungal presence and activity in various ecosystems.
Used in Agriculture:
(3β,22E)-ergosta-5,7,22-trien-3-yl D-glucopyranoside is used in agricultural applications, potentially serving as a natural fungicide or as a component in the development of fungicides to protect crops from fungal infections.
Used in Food Preservation:
(3β,22E)-ergosta-5,7,22-trien-3-yl D-glucopyranoside is used in the food preservation industry, possibly contributing to the development of natural preservatives to extend the shelf life of perishable goods and reduce spoilage.

Upstream product

• 57-87-4 Ergosterol 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 245550-14-5 2,3,4,6-tetra-O-acetyl-3-O-β-D-glucopyranosyl-ergosta-6,22-dien-5α,8α-epidioxy-3-β-ol 
• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-D-glucopyranoside 
• 2280-44-6 D-Glucose 
• 1354766-16-7 ergosterol-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside) 
• 627466-64-2 2,3,4,6-tetra-O-benzoyl-D-glucopyranose 
• 151767-11-2 2,3,4,5-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate 
• 149707-76-6 O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate 

Relevant academic research and scientific papers

Antitumor sterols from the mycelia of Cordyceps sinensis

Activity guided fractionations led to the isolation of two antitumor compounds 5α,8α-epidioxy-24(R)-methylcholesta-6,22-dien-3β-D- glucopyranoside and 5,6-epoxy-24(R)-methylcholesta-7,22-dien-3β-ol from the methanol extract of Cordyceps sinensis. Two previously known compounds, ergosteryl-3-O-β-D-glucopyranoside and 22-dihydroergosteryl-3-O-β-D- glucopyranoside were also isolated. The structures of hitherto unknown sterols were established by 1D and 2D NMR spectroscopic techniques with the former synthesized in order to confirm the identity of the sugar moiety by chemical correlation. The glycosylated from of ergosterol peroxide was found to be a greater inhibitor to the proliferation of K562, Jurkat, WM-1341, HL- 60 and RPMI-8226 tumor cell lines by 10 to 40% at 10 μg/ml than its previously identified aglycone, 5α,8α-epidioxy-24(R)-methylcholesta-6,22- dien-3β-ol.

Synthesis of ergosterol and 5,6-dihydroergosterol glycosides and their inhibitory activities on lipopolysaccharide-induced nitric oxide production

We have synthesized several glycosyl ergosterols and 5,6-dihydroergosterols (DHE) and examined their effects on production of nitric oxide (NO) and iNOS protein expression in LPS-treated RAW264.7 macrophage cells. Our results showed that DHE derivatives i

Highly efficient synthesis and antitumor activity of monosaccharide saponins mimicking components of Chinese folk medicine Cordyceps sinensis

Ergosterol 3-O-β-d-glucopyranoside (1a) and ergosterol 3-O-d-galactopyranoside (1b) were highly efficiently synthesized and evaluated for their inhibitory activities against two tumor cell lines. The structures of these compounds were extensively confirmed by 1H, 13C NMR, IR, and HRMS. Compounds 1a and 1b exhibited interesting cytotoxic profiles. The antitumor activity of compound 1a was higher than that of 1b.