627466-64-2

Upstream product

• 14218-11-2 2,3,4,6-tetra-O-benzoylglucosyl bromide 
• 79134-70-6 N-Benzyloxycarbonyl-L-serine 2-bromoethyl ester 
• 4814-80-6 acetylaminoacetonitrile 
• 22415-91-4 1,2,3,4,6-penta-O-benzoyl-α-D-glucopyranose 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-D-glucopyranoside 
• 105376-04-3 ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside 
• 2280-44-6 D-Glucose 
• 98-88-4 benzoyl chloride 
• 572-09-8 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 
• 492-61-5 β-D-glucose 
• 339276-12-9 2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl 1-(N-phenyl)-2,2,2-trifluoroacetimidate 
• 151767-11-2 2,3,4,5-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate 
• 1423987-57-8 C₃₆H₃₃NO₁₀ 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-β-D-glucopyranose 

Downstream Products

• 4163-40-0 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl fluoride 
• 4163-39-7 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranosyl fluoride 
• 228873-32-3 2,3,4,6-tetra-O-benzoyl-D-glucopyranos-1β-yl cyclohexyl carbonate 
• 228873-34-5 C₆₃H₅₈O₁₇ 
• 149707-75-5 2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate 
• 118579-76-3 methyl 4-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 128503-39-9 methyl 2,3,4-tri-O-benzoyl-6-O-(2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl)-α-D-glucopyranoside 
• 14218-11-2 2,3,4,6-tetra-O-benzoylglucosyl bromide 
• 428816-48-2 C₅₀H₃₇F₆NO₁₀S 
• 428816-48-2 2,3,4,6-tetra-O-benzoyl-α-D-glucopyranosyl p-trifluoromethylbenzylthio-p-trifluoromethylphenyl formimidate 
• 149707-76-6 O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate 
• 125135-28-6 methyl 6-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-2,3,4-tri-O-benzoyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

A novel and efficient deprotection of the allyl group at the anomeric oxygen of carbohydrates

Perfluoroalkylation with perfluoroalkyl iodide under sodium dithionite and sodium bicarbonate in acetonitrile/water followed by elimination in the presence of zinc powder and ammonium chloride in ethanol was disclosed to be an extremely mild and efficient procedure for deprotection of the anomeric allyl group of carbohydrates.

Synthesis of photolabile group protected anomeric acetals and its application in carbohydrate synthesis with the assistance of continuous flow photo-reactor

Selective deprotection of photolabile anomeric 2-nitrobenzyl acetals was achieved using continuous flow photo-reactor (UV radiation at 355 nm) in methanol-water. Various protecting groups such as acetyl, benzyl, benzoyl, benzylidine, TBS, etc. were found to be highly stable during the photolysis.

Ionic liquid-assisted catalysis for glycosidation of two triterpenoid sapogenins

In order to both investigate the universality of ionic liquid-based catalytic systems for synthesis of triterpene saponins and explore their effective application methods together with the catalytic behaviors of ionic liquids in related reactions by comparison between different initiators, oleanolic acid and ursolic acid were selected to establish a catalytic system for glycosylation in this study as typical representatives of pentacyclic triterpene sapogenins. As a result, it was found that the system of [C4mim][OTf] + TMSOTf in the reactions between the glycosyl receptors and donors showed obvious catalytic effects; also, the system was stable and could be recycled. The functions of IL include solvent, cocatalyst and stabilizer, simultaneously; thus, the current catalytic system is greener, simpler and more efficient. The reaction time was short, and only β-type products were obtained. This study offers a reference for developing a new glucoside synthesis technology and provides sufficient preliminary exploration and basic data for further large-scale applications.

Aralia saponin derivative as well as preparation method and application thereof (by machine translation)

The invention discloses an Aralia saponin derivative as well as a preparation method and application, thereof. A structure represented by the general formula (I). To the invention, oleanolic acid and four sugar, coffee acid or 3 - methoxy 4 - hydroxycinna

Aralia elata seem monomer saponin derivative and preparation method and use thereof

The invention discloses an aralia elata seem monomer saponin derivative and a preparation method and use thereof. The derivative has a structure represented by a general formula (I). Oleanolic acid orursolic acid, five kinds of sugars and caffeic acid are

ENDOSOMAL CLEAVABLE LINKERS

The present disclosure relates generally to cleavable linkers and uses thereof.

OFox imidates as versatile glycosyl donors for chemical glycosylation

Previously we communicated 3,3-difluoroxindole (HOFox)-mediated glycosylations wherein 3,3-difluoro-3H-indol-2-yl (OFox) imidates were found to be key intermediates. Both the in situ synthesis from the corresponding glycosyl bromides and activation of the

3 - monosaccharide acid oxygen glucoside oleanolic alkane type and wusu alkane triterpene saponin derivative and its preparation method and application

The invention discloses a 3-monouronic acid o-glycoside oleanane type and ursane type triterpenoid saponin derivative. The derivative has a structural formula as shown in the specification, wherein R4 is one of H atom, alkyl containing 1-10 carbons, alkyl

Regenerative glycosylation under nucleophilic catalysis

This article describes 3,3-difluoroxindole (HOFox)-mediated glycosylation. The uniqueness of this approach is that both the in situ synthesis of 3,3-difluoro-3H-indol-2-yl (OFox) glycosyl donors and activation thereof can be conducted in a regenerative fashion as is a typical reaction performed under nucleophilic catalysis. Only a catalytic amount of the OFox imidate donor and a Lewis acid activator are present in the reaction medium. The OFox imidate donor is constantly regenerated upon its consumption until glycosyl acceptor has reacted.

Synthesis and evaluation of four hederagenin glycosides as α-glucosidase inhibitor

The four hederagenin glycosides 1-4 were efficiently synthesized through one-pot sequential glycosylations with glycose 1-(trichloroacetimidate)s as donors, resulting in a significantly simplified synthetic procedure without isolation of glycosylation intermediates. The activity of the synthetic hederagenin glycosides 1-4 against α-glucosidase type IV was evaluated; hederagenin glycoside 4 containing an α-L-rhamnopyranosyl unit showed the best activity with an IC50 value of 47.9 μM. Copyright