130161-48-7Relevant academic research and scientific papers
DIRECT SYNTHESIS OF 2-SUBSTITUTED 5-FORMYLPYRIMIDINES AND RING TRANSFORMATION OF THEIR PHENYLHYDRAZONES INTO 4-FORMYL-1-PHENYLPYRAZOLE
Takagi, Kaname,Bajnati, Abdelilah,Hubert-Habart, Michel
, p. 1105 - 1109 (2007/10/02)
Triformylmethane (1) reacted with benzamidine, guanidine and S-methylisothiourea to give 2-substituted 5-formylpyrimidines (2a-c), whose phenylhydrazones (3a-c) readily underwent ring transformation into 4-formyl-1-phenylpyrazole (4) on heating in acidic methanol.
Direct syntheses of pyrazole-4-carbaldehydes and pyrimidine-5-carbaldehydes starting from triformylmethane.
Takagi, K.,Bajnati, A.,Hubert-Habart, M.
, p. 660 - 666 (2007/10/02)
Triformylmethane is transformed into the pyrazole-4-carbaldehydes 2, 4, 6, 7, 9, 11 and the pyrazole-4-carbaldehydes 8, 10, 12 by corresponding hydrazines, and into the pyrimidine-5-carbaldehydes 13, 14, 15 by appropriate amidines.
