120747-84-4

Basic information

• Product Name: 2-Amino-5-pyrimidinecarboxyaldehyde
• Synonyms: ASISCHEM C63547;2-AMINO-5-PYRIMIDINECARBOXYALDEHYDE;2-AMINO-PYRIMIDINE-5-CARBALDEHYDE;5-Pyrimidinecarboxaldehyde,2-amino-;5-Pyrimidinecarboxaldehyde, 2-amino- (9CI);2-Amino-5-pyrimidinecarbaldehyde;2-Amino-pyrimidine-5-carbaldehyde ,97%;2-aminopyrimidine-5-carbaldehyde(SALTDATA: FREE)
• CAS NO: 120747-84-4
• Molecular Formula: C₅H₅N₃O
• Molecular Weight: 123.11
• Product Categories: PYRIMIDINE;ALDEHYDE;NULL;Heterocycle-Pyrimidine series
• Mol File: 120747-84-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 209-214°C
• Boiling Point: 372.651 °C at 760 mmHg
• Flash Point: 179.173 °C
• Appearance: /
• Density: 1.371 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 1.99±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-5-pyrimidinecarboxyaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-pyrimidinecarboxyaldehyde(120747-84-4)
• EPA Substance Registry System: 2-Amino-5-pyrimidinecarboxyaldehyde(120747-84-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-43-36/37/38
• Safety Statements: 36/37-37/39-26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 120747-84-4(Hazardous Substances Data)

Usage

Chemical Properties

Light brown solid

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 28, p. 1281, 1991 DOI: 10.1002/jhet.5570280520

InChI:InChI=1/C5H5N3O/c6-5-7-1-4(3-9)2-8-5/h1-3H,(H2,6,7,8)

Upstream product

• 124-46-9 guanidine hydrogen carbonate 
• 2009-81-6 2-dimethylaminomethylene-1,3-bis(dimethylimonio)propane diperchlorate 
• 73312-68-2 1-(dimethylamino)ethylene-2,2-dicarboxaldehyde 
• 50-01-1 guanidine hydrochloride 
• 933702-55-7 2‐chloropyrimidine-5-carbaldehyde 
• 308348-93-8 2-amino-pyrimidine-5-carboxylic acid methyl ester 
• 18655-47-5 triformylmethane 

Downstream Products

• 862096-02-4 C₅H₆N₄O 
• 120747-85-5 (2-aminopyrimidin-5-yl)methanol 
• 258276-66-3 HIP-3 
• 258276-64-1 HIP-2 
• 257290-80-5 2-[5-(5,5-dimethyl-[1,3]dioxan-2-yl)-2-(toluene-4-sulfonylimino)-2H-pyrimidin-1-yl]-acetamide 

Relevant articles and documents

Benzimidazole derivatives, preparation methods and uses theirof

The present invention relates to benzimidazole compounds useful in treating for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention of one or more symptoms of cancer, transplant rejections. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK4 and/or CDK6, using the compounds provided herein.

Compounds and methods for kinase modulation, and indications therefor

Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereo

PIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to Compounds of Formula (I), compositions comprising the compounds, and methods of using the compounds to treat or prevent pain, diabetes, a diabetic complication, impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) in a patient.