13018-41-2

Usage

InChI:InChI=1/C12H18O6/c1-9(13)7-11(15)17-5-3-4-6-18-12(16)8-10(2)14/h3-8H2,1-2H3

Upstream product

• 110-63-4 Butane-1,4-diol 
• 141-97-9 ethyl acetoacetate 
• 105-45-3 acetoacetic acid methyl ester 
• 1694-31-1 tert-butyl acetoacetate 
• 674-82-8 4-methyleneoxetan-2-one 

Relevant academic research and scientific papers

Multicomponent Combinatorial Polymerization via the Biginelli Reaction

A multicomponent combinatorial polymerization method has been exploited as a new intersection between combinatorial chemistry, polymer chemistry, and organic chemistry. The tricomponent Biginelli reaction has been employed as a model multicomponent reaction (MCR) to efficiently prepare a library of polycondensates with continuously changed chain structure but different physical properties. The naturally increased reaction modules (monomers) directly doubled the number of polymers in the library, effectively improving the efficiency of polymer preparation. The glass transition temperatures (Tg) of those homologous polymers have been mapped for the first time to predict the Tg values of absent polymer homologues with good to excellent accuracy. Meanwhile, the Tg maps have also been used to reveal the regular change in Tg according to the polymer structure (linking group, monomer chain length, etc.), initially suggesting the academic significance of the multicomponent combinatorial polymerization system. We believe that the current research paves a straightforward way to synthesize new libraries of polymers via MCRs and might prompt the broader study of MCRs in interdisciplinary fields.

NOVEL COMPOSITIONS COMPRISING THE REACTION PRODUCT OF ACETOACETYLATED POLYOLS AND VANILLIN AND MELAMINE-FORMALDEHYDE RESIN COATING COMPOSITIONS THEREOF

This invention relates to novel compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to a method of making the novel compositions of the invention comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to novel curable coating compositions comprising at least one melamine-formaldehyde resin and the compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to a method of making the novel curable coating compositions of the invention comprising at least one melamine-formaldehyde resin and the compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to methods of applying curable coating compositions of the invention to substrates. The invention also relates to an article of manufacture comprising a curable coating composition of the invention and a method of making such article.

KETOCARBOXYLIC ACIDS, METHODS OF MANUFACTURE AND USES THEREOF

Ketocarboxylic acids such as levulinic acid can be efficiently purified in high yield by esterification with a hydrocarbon polyol to the corresponding polyketocarboxylic ester, which can be readily purified, for example recrystallized. After purification, the ketocarboxylic ester can be hydrolyzed to provide pure ketocarboxylic acid, or a salt thereof, after removal of the esterifying hydrocarbon polyol, or used for other synthetic transformations. Advantageously, the polyketocarboxylic esters, ketocarboxylic acids, and salts thereof produced by this method are obtained in high purity.

Assembling Polycyclic Bisguanidine Motifs Resembling Batzelladine Alkaloids by Double Tethered Biginelli Condensations

(Equation presented) Double tethered Biginelli condensations furnish linked polycyclic bisguanidines or bisureas. Alteration of the bis-β-ketoester component allows bispolycyclic guanidine motifs to be constructed that resemble natural batzelladine alkalo

Liquid oligomers containing acrylate unsaturation

The liquid oligomeric compositions of this invention are made by the Michael addition reaction of acetoacetate functional donor compounds with multifunctional acrylate receptor compounds where the equivalent ratios of multifunctional acrylate to acetoacetate vary from >/=1:1 to >/=13.2:1 depending on the functionality of both multifunctional acrylate and acetoacetate. Unuseable gelled or solid oligomer products occur below the claimed ranges. The liquid oligomers of this invention are further crosslinked to make coatings, laminates and adhesives.