130186-64-0Relevant articles and documents
Synthesis of 4-methyl-2,3-disubstituted quinoline scaffolds via environmentally benign Fe(iii) catalysed sequential condensation, cyclization and aromatization of 1,3-diketone and 2-ethynylaniline
Sivaraman, Mahalingam,Perumal, Paramasivan T.
, p. 52060 - 52066 (2014/12/10)
Environmentally benign Fe(iii)-catalysed sequential condensation, cyclization and aromatization of 1,3-diketone and 2-ethynylaniline derivatives to the substituted quinoline scaffolds with good to excellent yield in shorter reaction time is described. This journal is
Synthesis and crystal structure of 7,8-dihydroquinolino[2,3-a]acridine derivatives
Han, Guang-Fan,Wang, Rui-Hua,Zhang, Wen-Tao,Zhao, Yu-Yuan,Xing, Zheng,Dai, Wei
experimental part, p. 2492 - 2505 (2009/12/06)
Novel 9-amino-3-substituted-1,2,3,4-acridin-1-one derivatives and 9,14-diamino-7-substituted-7,8-dihydroquinolino[2,3-a]acridine derivatives were synthesized by the condensation reaction of 5-substituted-1,3-cyclohexanedione with 2-aminobenzonitrile and s
DERIVATIVES OF 9-AMINOACRIDINE HAVING PSYCHOTROPIC, ANTIAMNESTIC AND LIPID REGULATING PROPERTIES
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, (2008/06/13)
New chemical compounds, derivatives of 9-aminoacridine of general formula (I) where R = H, CH3; R1 = H, CH3, Br; R2 = H, CH3; R3 = alkyl-C1-C5, arylmethyl, diethylaminoethyl; X = C = O, CHOH; Y = CH2; X + Y = CH = CH; and their salts with organic and non-organic acids. The desired compounds are obtained by interaction of substituted nitriles of antranyl acid with dimedone with subsequent cyclization of intermediate enaminonitriles into corresponding ketones of 9-aminoacridine after the reduction of which and of their derivatives alkylated or aralkylated on the 9-amino group, the corresponding alcohols are obtained, after hydration of which 9-amino-3,4-dihydroacridines are obtained. When experimented on animals, the said derivatives of 9-aminoacridine have shown psychotropic, antiamnestic and lipid regulating properties, as well as a lower toxicity in comparison with known preparations.