130192-12-0Relevant academic research and scientific papers
Stereoselective intramolecular 6-exo-Heck reaction : A facile synthetic route to podocarpa-8,11,13-triene and diterpenoid resin acids intermediates
Mukhopadhyaya, Jayanta K.,Ghosh, Ajit K.,Ghatak, Usha Ranjan
, p. 835 - 837 (2007/10/03)
Intramolecular Heck reaction of the olefins 1a-c in the presence of sodium formate affords ca 3:1 mixtures of the respective trans- and cis-octahydrophenanthrenes 3a-c and 4a-c. Similar reaction of the olefmic ester 2 provides a 70:30 mixture of (±)-methyl desisopropyldehydroabietate 6 and (±)10-epi-methyl desoxypodocarpate 7.
Regioselective aryl radical cyclisation. Part 2. Synthesis of octahydro-1H-dibenzo[a,d]cycloheptenes through 7-endo ring closure
Ghosh, Ajit K.,Mukhopadhyaya, Jayanta K.,Ghatak, Usha Ranjan
, p. 2747 - 2755 (2007/10/03)
A simple convergent synthesis of trans- and cis-octahydro-1H-dibenzo[a,d]cycloheptenes 15a-c and 16a-c and 20a-c and 21a-c through implementation of a regioselective 7-endo-trig-aryl radical cyclisation of the respective 2-(o-bromoarylethyl)-1-methylenecy
Highly Regioselective 7-endo-Aryl Radical Cyclisation: Synthesis of Octahydro-2H-dibenzocycloheptenes
Ghosh, Ajit K.,Ghosh, Keya,Pal, Sitaram,Chatak, Usha Ranjan
, p. 809 - 811 (2007/10/02)
A highly efficient 7-endo-trig-aryl radical cyclisation of the alkene 6 and the vinylcyclohexanols 11a-d with tri-n-butyltin hydride leading to the respective octahydro-2H-dibenzocycloheptene derivatives 7 and 8 and 12a-d is reported.
Synthetic Studies towards Complex Diterpenoids. Part 18. Total Synthesis of (+/-)-Isopisiferin and the Related Compounds
Deb, Soumitra,Bhattacharjee, Gopa,Ghatak, Usha Ranjan
, p. 1453 - 1458 (2007/10/02)
A simple convergent and general method has been developed for the synthesis of (+/-)-isopisiferin (1c), a rearranged abietane diterpene, having a hexahydrodibenzocyclohepetene ring system, and the related model systems (1a) and (1b), through the respective enolisable tricyclic ketone mixtures (12c) and (13c), (12a) and (13a), and (12b) and (13b), obtained from the corresponding easily accessible 2-arylethyl-3,3-dimethylcyclohexanones (7c), (7a), and (7b).Demethylation of the styrenoid ethers (15b) and (15c) under acid conditions gave the tetracyclic dienones (17b) and (17c) through Ar1-5 cyclisation.
