20667-19-0

Usage

Uses

Used in Organic Chemistry:
METHYLTRIPHENYLPHOSPHONIUM IODIDE is used as a phase-transfer catalyst for facilitating and accelerating reactions between immiscible phases, which is crucial in various organic reactions.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, METHYLTRIPHENYLPHOSPHONIUM IODIDE is used as a catalyst in the synthesis of pharmaceuticals, aiding in the production of fine chemicals and enhancing the efficiency of chemical reactions necessary for drug development.
Used in Organic Reactions:
METHYLTRIPHENYLPHOSPHONIUM IODIDE is utilized in a variety of organic reactions, including alkylation, dealkylation, and cyanation reactions, where its ability to transfer reactants between phases is particularly beneficial for improving reaction rates and yields.

InChI:InChI=1/C19H18IP/c1-21(20,17-11-5-2-6-12-17,18-13-7-3-8-14-18)19-15-9-4-10-16-19/h2-16H,1H3

Upstream product

• 603-35-0 triphenylphosphine 
• 74-88-4 methyl iodide 

Downstream Products

• 130954-49-3 [2-Methylene-cyclopent-(E)-ylidenemethyl]-benzene 
• 2643-30-3 3-Vinylquinuclidine 
• 5676-29-9 (3,3-dimethylbut-1-en-2-yl)benzene 
• 130954-56-2 1-Methyl-4-[2-methylene-cyclohex-(E)-ylidenemethyl]-benzene 
• 130954-52-8 1-Methylene-2-[1-phenyl-meth-(E)-ylidene]-cyclooctane 
• 130954-51-7 1-Methylene-2-[1-phenyl-meth-(E)-ylidene]-cycloheptane 
• 1721-69-3 betulin diacetate 
• 19493-09-5 Methylenetriphenylphosphorane 
• 130192-12-0 3,3-dimethyl-1-methylene-2-phenethylcyclohexane 
• 139006-70-5 2-(4-methoxyphenethyl)-3,3-dimethyl-1-methylenecyclohexane 
• 130487-62-6 2-(3-isopropyl-4-methoxyphenethyl)-3,3-dimethyl-1-methylenecyclohexane 
• 122214-17-9 1-[2-Methylene-cyclohex-(E)-ylidenemethyl]-naphthalene 
• 107913-75-7 <<4-(1-methylethenyl)-1,3-phenylene>bis<<(oxymethylene)oxy>-2,1-ethanediyl>>bis(trimethylsilane) 
• 79409-46-4 Methyl (2S,3R,4S)-4-(1,3-Dioxolan-2-ylmethyl)-3,4-dihydro-2-(2,3,4,6-tetraacetyl-β-D-glucopyranosyloxy)-3-vinyl-2H-pyran-5-carboxylate 

Relevant academic research and scientific papers

Free-amine-directed alkenylation of C(sp2)-H and cycloamination by palladium catalysis

A new protocol for the palladium-catalyzed free-amine-directed alkenylation of C(sp2)-H bonds and cycloamination is described. Substituted biaryl-2-amines react with various alkenes, including electron-deficient alkenes, aryl alkenes and alkyl alkenes, to give the corresponding phenanthridines with exclusive regioselectivity. The use of α-branched styrenes leads to the formation of tricyclic compounds with a seven-membered amine ring. The method operates through a free-amine-directed alkenylation and a subsequent hydroamination cyclization reaction. Seven-membered cycloamination: A new protocol for the palladium-catalyzed free-amine-directed alkenylation of C(sp2)-H bonds and subsequent cycloamination is described (see scheme). Substituted biaryl-2-amines react with various alkenes to give the corresponding phenanthridines with exclusive regioselectivity. The use of α-branched styrenes leads to the formation of tricyclic compounds with a seven-membered amine ring. Copyright

A STUDY ON THE ADDITIVITY OF SUBSTITUENT EFFECTS IN THE TRIPHENYLPHOSPHONIUM SYSTEM

Additivity of substituent effects in the methyl-triphenylphosphonium system with substituents on different phenyl groups is tested.Results show that additive linear free energy relationships can be applied to describe multiple substituent effects in this system. Key words: Additivity substituent effects methyl-triphenylphosphonium system.