130195-74-3

Basic information

• Product Name: (1R,3R,4S)-2-[(1S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester
• Synonyms: (1R,3R,4S)-2-[(1S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester
• CAS NO: 130195-74-3
• Molecular Weight: 257.332
• Mol File: 130195-74-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (1R,3R,4S)-2-[(1S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R,4S)-2-[(1S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester(130195-74-3)
• EPA Substance Registry System: (1R,3R,4S)-2-[(1S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester(130195-74-3)

Safety Data

• Hazardous Substances Data: 130195-74-3(Hazardous Substances Data)

Upstream product

• 922-68-9 Methyl glyoxylate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 542-92-7 cyclopenta-1,3-diene 
• 618-36-0 rac-methylbenzylamine 
• 145774-77-2 methyl N-(1-phenylethyl)-α-iminoacetate 

Downstream Products

• 130194-96-6 (1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid methyl ester 
• 297143-31-8 (1S,3R,4R)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester 
• 297143-30-7 (1S,3R,4R)-2-(p-tert-butylphenylsulphonyl)-2-aza-bicyclo[2.2.1]heptane-3-caboxylic acid 
• 297143-32-9 (1S,3R,4R)-2-(4-tert-butylphenylsulfonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester 
• 347381-72-0 (1R,2R,6S,7R,9R)-4,4-Diethyl-8-[(S)-1-phenylethyl]-3,5-dioxa-8-azatricyclo[5.2.1.0^2,6]decane-9-carboxylic acid methyl ester 
• 347381-78-6 (R)-1-[(1R,2R,6S,7R,9R)-4,4-Dimethyl-8-((S)-1-phenyl-ethyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]dec-9-yl]-ethanol 
• 347381-71-9 (1R,2R,6S,7R,9R)-4,4-Dimethyl-8-[(S)-1-phenylethyl]-3,5-dioxa-8-azatricyclo[5.2.1.0^2,6]decane-9-carboxylic acid methyl ester 
• 347381-76-4 1-[(1R,2R,6S,7R,9R)-4,4-Dimethyl-8-[(S)-1-phenylethyl]-3,5-dioxa-8-aza-tricyclo[5.2.0^2,6]dec-9-yl]ethanone 
• 347381-74-2 (1R,2R,6S,7R,9R)-8-[(S)-1-Phenylethyl]-3,5-dioxa-8-azatricyclo[5.2.1.0^2,6]decane-9-carboxylic acid methyl ester 
• 347381-84-4 [(1R,2R,6S,7R,9R)-4,4-Dimethyl-8-((S)-1-phenyl-ethyl)-3,5-dioxa-8-aza-tricyclo[5.2.1.0^2,6]dec-9-yl]-methanol 

Relevant articles and documents

Multigram scale synthesis of a useful aza-Diels-Alder adduct in a one-step procedure

The aza-Diels-Alder reaction between a chiral imine (derived from methyl glyoxylate and (S)-(-)-1-phenylethylamine) and cyclopentadiene, in the presence of trifluoroacetic acid and boron trifluoride diethyl etherate have been performed in a one-step proce

A rigid dirhodium(II) carboxylate as an efficient catalyst for the asymmetric cyclopropanation of olefins

The dirhodium(II) complex 7 of (1S,3R,4R)-2-(p-tert-butylphenylsulphonyl)-2-aza-bicyclo[2.2.1]heptane-3- carboxylic acid (3) (or its enantiomer) was synthesised in four steps from cyclopentadiene, (R)- or (S)-phenylethylamine and methyl glyoxylate. Comple

Asymmetric aza-diels-alder reaction using the chiral 1-phenyl ethyl imine of methyl glyoxylate

The Diels-Alder reaction between cyclopentadiene and the chiral 1-phenyl-ethyl imine of methyl glyoxylate takes place very easily by activation with trifluoroacetic acid and boron trifluoride etherate to provide diastereoselectively (total face selectivit