130232-55-2Relevant academic research and scientific papers
On the stereochemistry of palmerolide A
Lebar, Matthew D.,Baker, Bill J.
, p. 8009 - 8010 (2007)
Degradative studies of the anticancer macrolide palmerolide A have resulted in re-assignment of the C-7, C-10, and C-11 stereocenters.
Dispiroketals in synthesis (part 9): Resolution of 1,2-diols using a C2-symmetric diphenyltetrahydrobipyran
Edwards,Entwistle,Ley,Owen,Perry
, p. 553 - 556 (2007/10/02)
A series of 1,2-diols were resolved by the enantioselective formation of the thermodynamically most stable dispiroketal using (2R,2'R) and (2S,2'S) 2,2'-diphenyl-3,3',4,4'-tetrahydro-6,6'-bi-2H-pyran 2 and 3. Deprotection was achieved using a metal ammonia reduction to liberate the resolved diols.
