130288-43-6Relevant articles and documents
Biomimetic studies towards the C28-C40 polycyclic domain of the azaspiracids
Aiguade, Josep,Hao, Junliang,Forsyth, Craig J.
, p. 817 - 820 (2007/10/03)
An acyclic intermediate representing a putative biomimetic precursor of the C28-C40 domain of the novel marine toxin azaspiracid was constructed convergently from C28-C34 and C35-C40 fragments. In studying the assembly of the C28-C34 dioxabicyclo[3.3.1]nonane system via an intramolecular hetero-conjugate addition upon a C34-C36 enone, a stereoselective C-Michael addition intervened to provide a highly substituted cyclohexane.