13034-76-9

Basic information

• Product Name: 1,2,3,3-Tetramethyl-2,3-dihydro-1H-indole
• Synonyms: 1,2,3,3-Tetramethyl-2,3-dihydro-1H-indole;1,2,3,3-Tetramethylindoline;2,3-Dihydro-1,2,3,3-tetramethyl-1H-indole
• CAS NO: 13034-76-9
• Molecular Formula: C₁₂H₁₇N
• Molecular Weight: 175.27
• Mol File: 13034-76-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 162 °C
• Boiling Point: 134-135 °C(Press: 15 Torr)
• Appearance: /
• Density: 0.932±0.06 g/cm3(Predicted)
• PKA: 6.35±0.60(Predicted)
• CAS DataBase Reference: 1,2,3,3-Tetramethyl-2,3-dihydro-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,3-Tetramethyl-2,3-dihydro-1H-indole(13034-76-9)
• EPA Substance Registry System: 1,2,3,3-Tetramethyl-2,3-dihydro-1H-indole(13034-76-9)

Safety Data

• Hazardous Substances Data: 13034-76-9(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Odor

Strong, fruity

Uses

a. Production of fragrances and perfumes
b. Synthesis of pharmaceuticals and other chemical products
c. Versatile building block in organic chemistry
d. Intermediate in the manufacture of dyes and specialty chemicals

Safety

Relatively safe chemical

Toxicity

Low toxicity

Environmental impact

Minimal environmental impact when used and handled properly

Upstream product

• 5418-63-3 1,2,3,3-tetramethyl-3H-indolium iodide 

Downstream Products

• 18781-58-3 2,3,3-trimethyl-2,3-dihydro-1H-indole 
• 1193463-03-4 2-[2-(4-hydroxyphenyl)ethenyl]-1,3,3-trimethyl-3H-indolium iodide 
• 61360-89-2 1,2,3,3-tetramethyl-6-nitroindoline 
• 80-05-7 BPA 
• 124548-76-1 1,3,3-trimethyl-2-methylene-6-nitroindoline 
• 124548-75-0 1,2,3,3-tetramethyl-4,6-dinitroindoline 
• 127986-14-5 1,2,3,3-tetramethyl-5-(N-benzoyl-1,2-dihydroisoquinol-1-yl)-indoline 
• 1082927-91-0 C₂₀H₂₄N₃O⁽¹⁺⁾*I^(1-) 
• 1640-39-7 2,3,3-trimethylindoleniune 
• 127986-17-8 1,3,3-trimethyl-2-methylene-5-(N-benzoyl-1,2-dihydroisoquinol-1-yl)indoline 
• 127986-22-5 1,3,3-trimethyl-2-methylene-5-(N-benzoyl-1,2-dihydroquinol-1-yl)indoline 

Relevant articles and documents

Synthesis and Properties of β-Phospha-trimethinecyanine Dyes with Indoline End Groups

Reaction of 1,3,3-trialkyl-2-methyleneindolines 4 and 5 with phosphorus(III) halides yields, by a twofold nucleophilic substitution, the halogeno-phosphanes 6a-c, which in turn react with trimethyloxonium tetrafluoroborate to give the β-phospha-trimethinecyanine dyes 3a, b.These β-phospha-cyanines 3a, b are the first higher-methinylogous representatives of the phosphamonomethinecyanine dyes 1, synthesized in 1964 by Dimroth and Hoffmann as the first compounds containing phosphorus in the oxidation state +3 and with coordination number 2. - The 1H-, 13C-, 31P-NMR- as well as the UV/VIS spectra of these β-phospha-cyanines 3a, b and of the analogous β-"carba"-, β-aza- and β-arsa-trimethinecyanines are discussed with respect to their constitution, configuration, and ?-electron-density distribution.