130368-98-8

Basic information

• Product Name: CarbaMic acid, N-(3-Methylenecyclobutyl)-, phenylMethyl ester
• Synonyms: CarbaMic acid, N-(3-Methylenecyclobutyl)-, phenylMethyl ester;(3-Methylenecyclobutyl)-Carbamic Acid Phenylmethyl Ester;(3-Methylenecyclobutyl)-Carbamic Acid Phenylmethyl Ester(WX685034)
• CAS NO: 130368-98-8
• Molecular Formula: C₁₃H₁₅NO₂
• Molecular Weight: 217.2637
• EINECS: -0
• Mol File: 130368-98-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 358.2±32.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• PKA: 12.01±0.20(Predicted)
• CAS DataBase Reference: CarbaMic acid, N-(3-Methylenecyclobutyl)-, phenylMethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMic acid, N-(3-Methylenecyclobutyl)-, phenylMethyl ester(130368-98-8)
• EPA Substance Registry System: CarbaMic acid, N-(3-Methylenecyclobutyl)-, phenylMethyl ester(130368-98-8)

Safety Data

• Hazardous Substances Data: 130368-98-8(Hazardous Substances Data)

Usage

General Description

CarbaMic acid, N-(3-Methylenecyclobutyl)-, phenylMethyl ester is an organic compound that is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It belongs to the class of carbaMic acids, which are known for their wide range of applications in organic chemistry. This specific compound contains a phenylMethyl ester group, which makes it a versatile intermediate for the development of various drugs and crop protection products. Its chemical structure and properties make it valuable in the production of complex molecules and its use as a synthetic intermediate in the pharmaceutical and agricultural industries.

Upstream product

• 136137-55-8 3-methylenecyclobutan-1-amine hydrochloride 
• 501-53-1 benzyl chloroformate 
• 15760-35-7 3-methylenecyclobutanecarbonitrile 
• 15760-36-8 3-methylenecyclobutane-1-carboxylic acid 
• 100-51-6 benzyl alcohol 

Downstream Products

• 130368-99-9 3-((N-benzyloxycarbonyl)amino)cyclobutanemethanol 
• 1363381-26-3 (1s,3r)-3-amino-1-methylcyclobutan-1-ol 
• 1363381-58-1 (cis)-3-amino-1-methylcyclobutan-1-ol 
• 1399085-90-5 3-(4-amino-5-{2-fluoro-5-[(S)-1-(tetrahydro-furan-2-yl)methoxy]-phenyl}-pyrrolo[2,3-d]pyrimidin-7-yl)-1-hydroxymethyl-cyclobutanol 
• 1272667-84-1 benzyl [3-hydroxy-3-(hydroxymethyl)cyclobutyl]carbamate 
• 171550-04-2 {3-[5-(benzylcarbamoyl-methyl)-1H-indol-3-yl]-cyclobutyl}-carbamic acid benzyl ester 
• 171549-95-4 {3-[5-(2-oxo-oxazolidin-4-ylmethyl)-1H-indol-3-yl]-cyclobutyl}-carbamic acid benzyl ester 

Relevant articles and documents

SUBSTITUTED QUINAZOLINES AS NLRP3 MODULATORS, FOR USE IN THE TREATMENT OF CANCER

The present invention provides compounds of Formula (I): Formula (I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

PYRROLO PYRIMIDINE DERIVATIVE

The compound represented by general formula (I) has strong Axl inhibition activity by means of a pyridone ring structure being introduced into a pyrrolo pyrimidine skeleton, and so the result can serve as a treatment agent for Axl-related diseases, for example cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glial tumors, renal disease, immune system disorders, and cardiovascular disease.

ETHER DERIVATIVES OF BICYCLIC HETEROARYLS

The invention relates to compounds of formula (I), wherein the substituents are as defined in the specification; to processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; such compounds as a medicament; such compounds for the treatment of a proliferative disease