1363381-26-3

Basic information

• Product Name: trans-3-Amino-1-methylcyclobutanol
• Synonyms: Cyclobutanol, 3-amino-1-methyl-, trans-
• CAS NO: 1363381-26-3
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.14844
• Mol File: 1363381-26-3.mol

Chemical Properties

• CAS DataBase Reference: trans-3-Amino-1-methylcyclobutanol(CAS DataBase Reference)
• NIST Chemistry Reference: trans-3-Amino-1-methylcyclobutanol(1363381-26-3)
• EPA Substance Registry System: trans-3-Amino-1-methylcyclobutanol(1363381-26-3)

Safety Data

• Hazardous Substances Data: 1363381-26-3(Hazardous Substances Data)

Upstream product

• 130368-98-8 N-(benzyloxycarbonyl)-3-methylenecyclobutanamine 
• 15760-36-8 3-methylenecyclobutane-1-carboxylic acid 
• 15760-35-7 3-methylenecyclobutanecarbonitrile 

Downstream Products

• 1391625-25-4 C₅₂H₅₉ClN₈O₆S₂ 

Relevant articles and documents

SUBSTITUTED QUINAZOLINES AS NLRP3 MODULATORS, FOR USE IN THE TREATMENT OF CANCER

The present invention provides compounds of Formula (I): Formula (I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

CHEMICAL COMPOUNDS AS H-PGDS INHIBITORS

A compound of formula (I) wherein R1, R2, R3, R4, X, Y, and A are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.