13037-63-3

Basic information

• Product Name: 2,4-DIBROMOPHENYL ISOTHIOCYANATE
• Synonyms: 2,4-DIBROMOPHENYL ISOTHIOCYANATE
• CAS NO: 13037-63-3
• Molecular Formula: C₇H₃Br₂NS
• Molecular Weight: 292.98
• Mol File: 13037-63-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 60-62°C
• Appearance: /
• CAS DataBase Reference: 2,4-DIBROMOPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIBROMOPHENYL ISOTHIOCYANATE(13037-63-3)
• EPA Substance Registry System: 2,4-DIBROMOPHENYL ISOTHIOCYANATE(13037-63-3)

Safety Data

• Hazardous Substances Data: 13037-63-3(Hazardous Substances Data)

Upstream product

• 463-71-8 thiophosgene 
• 615-57-6 2,4-dibromo-aniline 
• 594-42-3 chlorothio-trichloro-methane 
• 1985-12-2 4-Bromophenyl isothiocyanate 
• 75-15-0 carbon disulfide 
• 1189351-07-2 C₆H₁₅N*C₇H₅Br₂NS₂ 
• 23373-04-8 2',4'-dibromoacetanilide 
• 454426-44-9 N-(2,4-dibromo-phenyl)-N'-phenyl-thiourea 

Downstream Products

• 1161730-15-9 N-(2,4-dibromophenyl)-3-hydroxyazetidine-1-carbothioamide 
• 1189350-92-2 6-bromo-2-(phenylthio)-1,3-benzothiazole 
• 1199943-81-1 6-bromo-2-phenoxy-1,3-benzothiazole 
• 863001-17-6 4-(6-bromobenzo[d]thiazol-2-yl)morpholine 
• 1580491-04-8 C₁₀H₁₂Br₂N₂OS 
• 90617-75-7 (2,4-dibromo-phenyl)-thiourea 
• 16691-32-0 1-(2,4-Dibrom-phenyl)-4-S-methyl-4-isodithiobiuret 

Relevant articles and documents

Isothiocyanate-Directed Ortho-Selective Halogenation of Arenes via C–H Functionalization

Abstract: Ortho-selective halogenation of arenes via C–H functionalization has been described under mild reaction conditions. In this reaction Cu(II)X2 was used as a halide source. It is a simple, general and efficient method for the synthesis of 2-halo aromatic isothiocyanates. All the reactions are carried out under optimized reaction conditions to provide their respective desired products in good to high yield. Graphical Abstract: We have developed a general, simple and efficient method for the synthesis of 2-halo arylisothiocyanates from isothiocyanates through ortho-selective halogenation under mild reaction conditions. Cu(II)X2 was used as a halide source for this methodology. All the reactions are carried out under optimized reaction conditions to provide their respective desired products in good to high yield. [Figure not available: see fulltext.].

Convenient synthesis of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles with 1 mol% CuCl2·2H2O as catalyst in water

A convenient and efficient procedure for the synthesis of benzo[4,5]thiazolo [2,3-c][1,2,4]triazoles has been developed via a tandem intermolecular C-N bond and intramolecular C-S bond formation sequence from o-bromo-arylisothiocyanates and aroylhydrazides. A series of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles were provided in excellent overall yields with 1 mol% CuCl2·2H2O/1 mol% 1,10-phenanthroline as the catalyst and water as the solvent. This journal is

Structure-activity relationship of dihydroimidazo-, dihydropyrimido, tetrahydrodiazepino-[2,1-b]-thiazoles, and -benzothiazoles as an acylation catalyst

Cyclic isothioureas 1, 2, 3, and 4 were synthesized through a four-step procedure from the corresponding ortho-bromoanilines 10 via Pd- or Cu-catalyzed cyclization-benzothiazole formation. Nonbenzo analogues 7, 8, and 9 were synthesized by a condensation reaction of cyclic thioureas 15 and α-bromoacetophenones 14. Investigations of the acylation reactions of 1-phenylethanol with acid anhydrides in the presence of these cyclic isothiourea catalysts revealed their structure-activity relationships. Remarkable electronic effects resulting from substituent(s) on a benzo or phenyl moiety and the influence of the size of the annulating ring were observed. Introduction of an electron-donating substituent(s) enhanced the reaction rate. A few substitution effects on chiral catalysts of type 3 and 7 were also studied.