130384-98-4

Basic information

• Product Name: N-Boc-Benzotriazole
• Synonyms: AKOS 39;N-BUTOXYCARBONYLBENZOTRIAZOLE;N-BOC-BENZOTRIAZOLE;1-(TERT-BUTOXYCARBONYL)BENZOTRIAZOLE;1-(T-BUTOXYCARBONYL)BENZOTRIAZOLE;tert-Butyl 1H-benzo[d][1,2,3]triazole-1-carboxylate
• CAS NO: 130384-98-4
• Molecular Formula: C₁₁H₁₃N₃O₂
• Molecular Weight: 219.24
• Mol File: 130384-98-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 324.405 °C at 760 mmHg
• Flash Point: 149.995 °C
• Appearance: /
• Density: 1.222 g/cm³
• Vapor Pressure: 0.000246mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: N-Boc-Benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-Benzotriazole(130384-98-4)
• EPA Substance Registry System: N-Boc-Benzotriazole(130384-98-4)

Safety Data

• Hazardous Substances Data: 130384-98-4(Hazardous Substances Data)

Usage

General Description

N-Boc-Benzotriazole, also known as N-tert-butoxycarbonyl-benzotriazole, is a chemical compound used as a photoinitiator in the production of photopolymers and as a stabilizer for polymers. It is a white to off-white crystalline powder that is insoluble in water but soluble in common organic solvents. N-Boc-Benzotriazole is known for its ability to absorb UV radiation and initiate reactions in polymerization processes. It is also used as an inhibitor in the synthesis of peptides and as a reagent in organic chemistry. Additionally, it is known for its low volatility and high thermal stability, making it suitable for a wide range of industrial applications.

InChI:InChI=1/C11H13N3O2/c1-11(2,3)16-10(15)14-9-7-5-4-6-8(9)12-13-14/h4-7H,1-3H3

Upstream product

• 65095-13-8 1-benzotriazolecarboxylic acid chloride 
• 75-65-0 tert-butyl alcohol 
• 95-54-5 1,2-diamino-benzene 
• 146651-75-4 tert–butyl (2–aminophenyl)carbamate 
• 95-14-7 1,2,3-Benzotriazole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 34619-03-9 tert-butyldicarbonate 

Downstream Products

• 21887-64-9 N₂-(tert-butoxycarbonyl)-L-ornithine 
• 2389-60-8 Z-Lys(Boc)-OH 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 4530-20-5 BOC-glycine 
• 13139-14-5 Boc-Trp-OH 
• 1385775-56-3 N-Boc-L-Cys(S-(4-NO₂-Bz))-OH 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 95-14-7 1,2,3-Benzotriazole 
• 2900-27-8 (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid 

Relevant articles and documents

Tert -Butyl nitrite mediated nitrogen transfer reactions: Synthesis of benzotriazoles and azides at room temperature

A conversion of o-phenylenediamines into benzotriazoles was achieved at room temperature using tert-butyl nitrite. The optimized conditions are also well suited for the transformation of sulfonyl and acyl hydrazines into corresponding azides. This protocol does not require any catalyst or acidic medium. The desired products were obtained in excellent yields in a short span of time.

PROCESS FOR THE PREPARATION OF ε-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES

A process for the preparation of ω-alkoxycarbonylamino-α-aminoacids and α,ω orthogonally diprotected diaminoacids from α,ω-diaminoacids using 1- alkoxycarbonylbenzotriazoles as protecting agents is disclosed. In an alternative embodiment, carbamoylating agents in the presence of benzotriazoles are used instead of 1-alkoxycarbonylbenzotriazoles. This reaction is preferably applied to the preparation of ε- alkoxycarbonyllysines from lysine. A process for the preparation of t-butoxycarbonylbenzotriazoles and novel complexes of ω-alkoxycarbonylamino-α-aminoacids with benzotriazoles are also disclosed.